Steroids

Integrative blockwise sparse analysis for tissue characterization and classification.

The topic of sparse representation of samples in high dimensional spaces has attracted growing inter...

Effect of congenital adrenal hyperplasia treated by glucocorticoids on plasma metabolome: a machine-learning-based analysis.

BACKGROUND: Congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency leads to impaired ...

Probing the degradation of pharmaceuticals in urine using MFC and studying their removal efficiency by UPLC-MS/MS.

Nutrient recovery from source-separated human urine has attracted interest as it is rich in nitrogen...

Discriminating stress from rest based on resting-state connectivity of the human brain: A supervised machine learning study.

Acute stress induces large-scale neural reorganization with relevance to stress-related psychopathol...

Patient discussions of glucocorticoid-related side effects within an online health community forum.

Automatic opportunistic osteoporosis screening using low-dose chest computed tomography scans obtained for lung cancer screening.

OBJECTIVE: Osteoporosis is a prevalent and treatable condition, but it remains underdiagnosed. In th...

Decoding rejuvenating effects of mechanical loading on skeletal aging using in vivo μCT imaging and deep learning.

Throughout the process of aging, dynamic changes of bone material, micro- and macro-architecture res...

Radiomics for classification of bone mineral loss: A machine learning study.

PURPOSE: The purpose of this study was to develop predictive models to classify osteoporosis, osteop...

New Insights and Methods in the Approach to Thalassemia Major: The Lesson From the Case of Adrenal Insufficiency.

Thalassemia Major (TM) is a complex pathology that needs a highly skilled approach. Endocrine comor...

Machine Learning Approach for Fluconazole Resistance Detection Using Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry.

causes life-threatening systemic infections in immunosuppressed patients. These infections are comm...

Unsupervised machine learning for the discovery of latent disease clusters and patient subgroups using electronic health records.

Machine learning has become ubiquitous and a key technology on mining electronic health records (EHR...

Effects of post-weaning supplementation of immunomodulatory feed ingredient on body weight and cortisol concentrations in program-fed beef heifers.

The objective of this study was to determine the effects of an immunomodulatory feed ingredient duri...

Road Transport of Late-Pregnant Mares Advances the Onset of Foaling.

Cortisol is involved in the initiation of parturition and we hypothesized that increased maternal co...

Effect of experimental infectious bursal disease virus on clinical signs and pathogenesis of avian influenza virus HN in turkey by real time PCR.

Infectious bursal disease virus (IBDV) in turkeys may result in immunosuppression, and inability of ...

Effect of Phaleria Macrocarpa Flesh Fruits Extract on MDA Level, SGOT and SGPT Activity in Serum of Experimental Rats Contaminated by Cd (II) Ion.

BACKGROUND: Cd (II) ion is a heavy metal that has a toxic ability in the human body. P. macrocarpa h...

Computational modeling of the monoaminergic neurotransmitter and male neuroendocrine systems in an analysis of therapeutic neuroadaptation to chronic antidepressant.

Second-line depression treatment involves augmentation with one (rarely two) additional drugs, of ch...

Diagnostic and Gradation Model of Osteoporosis Based on Improved Deep U-Net Network.

The measurement of bone mineral density for osteoporosis has always been the focus of researchers be...

The exploration of feature extraction and machine learning for predicting bone density from simple spine X-ray images in a Korean population.

OBJECTIVE: Osteoporosis is hard to detect before it manifests symptoms and complications. In this st...

Rapid Stability Indicating HPLC Method for the Analysis of Leflunomide and Its Related Impurities in Bulk Drug and Formulations.

OBJECTIVES: Leflunomide (LFNM) is a drug that belongs to isoxazole derivatives and has immunosuppres...

Steroid identification via deep learning retention time predictions and two-dimensional gas chromatography-high resolution mass spectrometry.

Untargeted steroid identification represents a great analytical challenge even when using sophistica...

The Use of Transdermal Estrogen in Castrate-resistant, Steroid-refractory Prostate Cancer.

BACKGROUND: Androgen-deprivation therapy is the mainstay of treatment for metastatic prostate cancer...