Strokes

Accurate and fast feature selection workflow for high-dimensional omics data.

We are moving into the age of 'Big Data' in biomedical research and bioinformatics. This trend could be encapsulated in this simple formula: D = S * F, where the volume of data generated (D) increases in both dimensions: the number of samples (S) and the number of sample features (F). Frequently, a typical omics classification includes redundant and irrelevant features (e.g. genes or proteins) tha...

Biomarker and shear stress in secondary pediatric pulmonary hypertension.

Background/aim: Endothelial dysfunction, tissue damage, inflammation, and microthrombosis are involved in the pathogenesis of pulmonary hypertension (PH), which may be present as a complication of congenital heart diseases. This study aims to identify how indicators of endothelial dysfunction (shear stress), tissue damage (brain natriuretic peptide and troponin T), inflammation (C-reactive protein...

Detecting atrial fibrillation by deep convolutional neural networks.

BACKGROUND: Atrial fibrillation (AF) is the most common cardiac arrhythmia. The incidence of AF increases with age, causing high risks of stroke and i...

Netrin-1 Ameliorates Blood-Brain Barrier Impairment Secondary to Ischemic Stroke via the Activation of PI3K Pathway.

Secondary impairment of blood-brain barrier (BBB) occurs in the remote thalamus after ischemic stroke. Netrin-1, an axonal guidance molecule, presents...

Clinical and Imaging Outcomes of Endovascular Therapy in Patients with Acute Large Vessel Occlusion Stroke and Mild Clinical Symptoms.

BACKGROUND: The minimal stroke severity justifying endovascular intervention remains elusive. However, a significant proportion of patients presenting...

Proprioceptive assessment in clinical settings: Evaluation of joint position sense in upper limb post-stroke using a robotic manipulator.

Proprioception is a critical component for motor functions and directly affects motor learning after neurological injuries. Conventional methods for i...

Endothelial markers in high altitude induced systemic hypertension (HASH) at moderate high altitude.

BACKGROUND: Chronic intermittent hypoxia is known to induce systemic arterial hypertension whereas chronic hypoxia causes pulmonary arterial hypertens...

Predicting the sources of impaired wh-question comprehension in non-fluent aphasia: A cross-linguistic machine learning study on Turkish and German.

This study investigates the comprehension of wh-questions in individuals with aphasia (IWA) speaking Turkish, a non-wh-movement language, and German, ...

Continuous betadine-bacitracin irrigation for vascular graft infections: A case series.

The aim of the study was to conduct a retrospective chart review of patients who underwent betadine/bacitracin continuous irrigation (BBCI) for vascul...

Spectrophotometric analysis of thrombolytic activity: SATA assay.

Measurement of thrombolytic activity is crucial for research and development of novel thrombolytics. It is a key factor in the assessment of the effe...

Compliant Buckled Foam Actuators and Application in Patient-Specific Direct Cardiac Compression.

We introduce the use of buckled foam for soft pneumatic actuators. A moderate amount of residual compressive strain within elastomer foam increases th...

Loculated transudative pleural effusion masquerading as right upper lobe consolidation in a haemodialysis patient.

Pleural effusion is a common encounter in renal failure patients and frequently possess a diagnostic challenge to clinician especially when it was exu...

Robot Training With Vector Fields Based on Stroke Survivors' Individual Movement Statistics.

The wide variation in upper extremity motor impairments among stroke survivors necessitates more intelligent methods of customized therapy. However, c...

Noninvasive Evaluation of Portal Hypertension Using a Supervised Learning Technique.

Portal hypertension (PHT) is a key event in the evolution of different chronic liver diseases and leads to the morbidity and mortality of patients. Th...

Pneumatic Displacement of Submacular Hemorrhage with Subretinal Air and Tissue Plasminogen Activator: Initial United States Experience.

PURPOSE: To present the initial multicenter experience of using subretinal air injection in combination with tissue plasminogen activator (tPA) at the...

Deep learning guided stroke management: a review of clinical applications.

Stroke is a leading cause of long-term disability, and outcome is directly related to timely intervention. Not all patients benefit from rapid interve...

Delineation of the ischemic stroke lesion based on watershed and relative fuzzy connectedness in brain MRI.

Precise segmentation of stroke lesions from brain magnetic resonance (MR) images poses a challenging task in automated diagnosis. In this paper, we pr...

The Combined Effects of Adaptive Control and Virtual Reality on Robot-Assisted Fine Hand Motion Rehabilitation in Chronic Stroke Patients: A Case Study.

Robot-assisted therapy is regarded as an effective and reliable method for the delivery of highly repetitive training that is needed to trigger neurop...

Analysis of deep learning methods for blind protein contact prediction in CASP12.

Here we present the results of protein contact prediction achieved in CASP12 by our RaptorX-Contact server, which is an early implementation of our de...

Clopidogrel-Induced Insulin Autoimmune Syndrome: A Newly Recognized Cause of Hypoglycemia in a Patient Without Diabetes.

Insulin autoimmune syndrome (IAS), defined as hyperinsulinemic hypoglycemia with high titers of anti-insulin antibodies, is frequently reported in Jap...