Latest AI and machine learning research in transplantation for healthcare professionals.
Emerging evidence links reactive oxygen species modulator 1 (ROMO1), a key mitochondrial ROS regulator, to rheumatoid arthritis (RA) pathogenesis. However, its exact mechanism remains elusive given the conflicting evidence about its specific function. We used a four-level integrative framework combining multi-omics data and literature‑supported mechanistic inference. At the genetic level, Mendelia...
BACKGROUND: Systemic amyloidosis is a progressive disease in which misfolded protein toxicity and deposition lead to organ dysfunction. Early diagnosis is essential to enable timely treatment and prevent irreversible organ damage, yet the disease remains underrecognized. Although advances in imaging and biomarkers have raised suspicion in appropriate contexts, a major barrier is the absence of cle...
Advances in digital pathology, image analysis, and artificial intelligence (AI) are rapidly transforming how pathologists and researchers interact wit...
MELD-based scores do not fully account for systemic and metabolic risk in liver transplant candidates, with notable gaps for those with metabolic dysf...
Industrial wastewater treatment poses significant challenges because effluents vary in composition, containing dissolved salts, organic contaminants, ...
Multiple myeloma (MM) is a malignant blood cancer marked by severe bone destruction and immune microenvironment disruption. Yet relapse and drug resis...
Pancreatic adenocarcinoma (PAAD) remains one of the most lethal cancers, largely due to the lack of reliable diagnostic biomarkers. Through integrativ...
To explore the role of N4-acetylcytidine (ac4C)-related genes (acRGs) in colon adenocarcinoma (COAD) and identify reliable prognostic biomarkers and p...
BackgroundSepsis-associated acute kidney injury (SA-AKI) is highly heterogeneous with controversial optimal renal replacement therapy (RRT) strategies...
Age-related decline in muscle health is commonly defined using cut-offs for strength, muscle quantity or quality, and physical performance. These meas...
We aimed to systematically analyze the historical evolution of artificial intelligence (AI) in end-stage renal disease (ESRD) management and propose a...
BACKGROUND: Artificial intelligence (AI) is increasingly being applied across medical disciplines to enhance clinical decision-making. However, its us...
Cancer cells exhibit metabolic reprogramming, most notably the Warburg effect, which underscores their heightened dependency on glucose uptake facilit...
Neoantigen vaccines have rekindled interest in therapeutic cancer vaccination, yet their clinical efficacy remains constrained by imperfect antigen pr...
BACKGROUND: Renal transplantation is the preferred treatment for end-stage chronic kidney disease but requires lifelong immunosuppression, increasing ...
Solid tumors, the most prevalent form of malignancy, pose therapeutic challenges distinct from hematologic malignancies due to their complex biology, ...
It has been known since at least the 1980's that the structure and chemistry of membranes and membrane proteins are matched. Exploiting this fact, a g...
Cryo-electron microscopy (cryo-EM) micrographs are frequently contaminated by carbon edges, ice crystals, ethane bubbles and other high-contrast artif...
This paper addresses the path tracking control problem for intelligent vehicles subject to parametric uncertainties, unmodeled dynamics, and external ...
Xenotransplantation represents a potential solution to the persistent global organ shortage, yet its clinical application remains stalled by complex i...