Transplantation

Latest AI and machine learning research in transplantation for healthcare professionals.

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Diffusion-Based Quality Control of Medical Image Segmentations across Organs.

Medical image segmentation using deep learning (DL) has enabled the development of automated analysis pipelines for large-scale population studies. However, state-of-the-art DL methods are prone to hallucinations, which can result in anatomically implausible segmentations. With manual correction impractical at scale, automated quality control (QC) techniques have to address the challenge. While pr...

Jul 17 2026 42467579

AI-SOFA: An EMR-integrated Nursing Informatics-driven Decision Support System for Mortality Risk-informed ICU Clinical Decision-making.

Accurate and timely mortality prediction is essential for nursing clinical decision-making in intensive care units (ICUs). Although the Sequential Organ Failure Assessment (SOFA) score is widely used to evaluate organ dysfunction, its manual calculation limits routine application in fast-paced clinical environments. This study aimed to enhance ICU system-level safety and workflow efficiency by ref...

Jul 17 2026 42467996
Prospective Validation of Multi-week Inpatient Census Forecasting for Pediatric HSCT and Cellular Therapy.

BACKGROUND: Accurate inpatient census forecasting is important for cell therapy and blood and marrow transplantation (BMT) programs because bed capaci...

Jul 17 2026 42468827
Neoadjuvant Chemoradiotherapy on Postoperative Complications of Rectal Cancer: A Retrospective Study Integrating MRI Radiomics and Deep Learning.

Neoadjuvant chemoradiotherapy (nCRT) is standard for locally advanced rectal cancer but increases postoperative complication (POC) risks due to tissue...

Jul 17 2026 42469490
Modeling symptom-acupoint interactions via a heterogeneous graph learning framework for intelligent acupoint recommendation.

OBJECTIVE: Acupuncture prescriptions involve complex compatibility mechanisms grounded in multi-symptom and multi-acupoint interactions, embodying mil...

Jul 16 2026 42464393
AI Models Could Improve Diagnosis and Care for Rare Diseases.

Rare diseases are often critically underfunded, leaving many patients without timely diagnosis and treatment. In this News and Perspectives article, J...

Jul 16 2026 42464796
Unlocking the Chemical Space for Rechargeable Batteries with a Generative Solvent Design System.

Electrolyte discovery for rechargeable batteries today relies on heuristic trial-and-error or high-throughput screening of existing molecules. Here, w...

Jul 16 2026 42460978
Next-generation precision oncology in microsatellite stable colorectal cancer: integrated targeting beyond RAS and RAF.

The therapeutic landscape of colorectal cancer (CRC) has evolved with the identification of molecular subtypes, including mismatch repair-deficient/mi...

Jul 16 2026 42462280
Comprehensive analysis of the association between perfluorooctanoic acid exposure and osteosarcoma progression.

Perfluorooctanoic acid (PFOA), a persistent environmental pollutant, represents a chronic environmental stressor, yet its role in osteosarcoma progres...

Jul 16 2026 42462996
Screening of core targets for Di(2-ethylhexyl) Phthalate-related gastric cancer based on machine learning, molecular docking, and SHAP analysis.

PURPOSE: Given the existing uncertainties regarding the link between Di(2-ethylhexyl) phthalate (DEHP) exposure and gastric cancer (GC) progression, t...

Jul 16 2026 42461936
Translating machine learning predictions into meaningful risk estimates to support clinical decisions: a post hoc analysis of chronic obstructive pulmonary disease adverse outcomes using unified auto clinical scores.

OBJECTIVE: The successful integration of Machine Learning (ML) models into clinical practice remains limited, as they often lack the standardized, qua...

Jul 15 2026 42454974
Improving hard-to-place kidney allocation: A machine learning approach to center ranking.

Kidney transplantation is the preferred treatment for end-stage renal disease, yet donor scarcity and inefficiencies in allocation systems create majo...

Jul 15 2026 42455365
Single-Cell and Bulk RNA Sequencing Reveal MCL1 as a Key Regulator of Mitochondrial Function in Liver Ischemia-Reperfusion Injury.

Liver ischemia-reperfusion injury (LIRI), a significant complication following liver transplantation and surgical procedures, remains inadequately add...

Jul 15 2026 42361133
Atomic Uncertainty Pinpoints Critical Failure Structures for Trustworthy Molecular Property Prediction.

Accurate prediction of molecular properties is essential for accelerating drug discovery, yet current deep learning methods generally lack reliable un...

Jul 14 2026 42447216
Why physicians resist artificial intelligence: A systematic review through the lens of diffusion of innovations.

BACKGROUND: Artificial intelligence (AI) enabled systems hold significant promise for transforming health care delivery. These technologies are freque...

Jul 14 2026 42447332
Time, Tissue, and Team: Reframing Transbronchial Biopsy in Lung Transplantation as an Integrated Diagnostic System.

Despite remarkable advances in transplant pathology, molecular diagnostics, imaging, and biomarker discovery, uncertainty remains an intrinsic feature...

Jul 14 2026 42448010
An Interactive Virtual Nephrologist to Engage Patients With Advanced CKD About Transplantation.

RATIONALE & OBJECTIVE: Despite advantages in survival and quality of life with kidney transplantation (KT) compared to other treatments for kidney fai...

Jul 14 2026 42448023
Integrative multi-omics reveals MHC class II-mediated neuroinflammation and systemic metabolic dysregulation as transdiagnostic drivers in major brain disorders.

Psychiatric, neurodevelopmental, and neurodegenerative disorders, including Alzheimer's disease (AD), attention-deficit/hyperactivity disorder (ADHD),...

Jul 14 2026 42448663
AI-based organ weight estimation from postmortem computed tomography.

Accurate organ weight determination is essential in forensic autopsy. Postmortem computed tomography (CT) combined with Artificial Intelligence (AI)-b...

Jul 14 2026 42443313
Improved 28-day mortality prediction by combining Lactate Dehydrogenase-to-Albumin Ratio(LAR) to lactate-enhanced Sequential Organ Failure Assessment (SOFA) score in patients with sepsis: a derivation and validation study.

BACKGROUND: Fast risk stratification is essential for patients with sepsis, a life-threatening condition associated with high mortality, as it guides ...

Jul 14 2026 42443791
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