Transplantation

Generation of safe and therapeutically effective human induced pluripotent stem cell-derived hepatocyte-like cells for regenerative medicine.

Hepatocyte-like cells (HLCs) differentiated from human induced pluripotent stem (iPS) cells are expected to be applied for regenerative medicine. In this study, we attempted to generate safe and therapeutically effective human iPS-HLCs for hepatocyte transplantation. First, human iPS-HLCs were generated from a human leukocyte antigen-homozygous donor on the assumption that the allogenic transplant...

Low-dose Rituximab therapy in resistant idiopathic membranous nephropathy: single-center experience.

BACKGROUND: Persistent significant proteinuria has been associated with increased risk of progression to end-stage kidney disease in patients with idiopathic membranous nephropathy (IMN). Rituximab (RTX) therapy has given encouraging results in IMN, but most of the studies have used a higher dose, which is limited by the high cost as well as a potential increased risk of infections. Our study aime...

DNA Implementation of Fuzzy Inference Engine: Towards DNA Decision-Making Systems.

Decision-making systems are an integral part of any autonomous device. With the recent developments in bio-nanorobots, smart drugs, and engineered vir...

Predicting Organ Toxicity Using in Vitro Bioactivity Data and Chemical Structure.

Animal testing alone cannot practically evaluate the health hazard posed by tens of thousands of environmental chemicals. Computational approaches mak...

Protracted severe systemic cytomegalovirus disease in an immunosuppressed patient with ulcerative colitis.

A 33-year-old man with ulcerative colitis presented with 5-day history of fever, night sweats, abdominal pain and increased stool frequency. He was on...

Performance of neural networks for localizing moving objects with an artificial lateral line.

Fish are able to sense water flow velocities relative to their body with their mechanoreceptive lateral line organ. This organ consists of an array of...

Evaluation of thyme and ajwain as antibiotic growth promoter substitutions on growth performance, carcass characteristics and serum biochemistry in Japanese quails ().

The present study was to evaluate thyme and ajwain as antibiotic growth promoter substitutions on growth performance, carcass characteristics and seru...

Re: Pediatric Robot-Assisted Redo Pyeloplasty with Buccal Mucosa Graft: A Novel Technique.

Compatibility, Stability, and Efficacy of Vancomycin Combined With Gentamicin or Ethanol in Sodium Citrate as a Catheter Lock Solution.

Indwelling catheters deliver lifesaving medical treatments for many chronically ill patients but are frequently a source of infection. Treatment may ...

Managing Drug Interactions in Cancer Therapy: A Guide for the Advanced Practitioner.

Mrs. P is a 30-year-old woman who presented to our bone marrow transplant program with myelodysplastic syndrome (MDS). She received a haploidentical a...

Comparison of hydrocortisone and prednisone in the glucocorticoid replacement therapy post-adrenalectomy of Cushing's Syndrome.

Cushing's syndrome requires glucocorticoid replacement following adrenalectomy. Based on a simplified glucocorticoid therapy scheme and the peri-opera...

Is Romantic Desire Predictable? Machine Learning Applied to Initial Romantic Attraction.

Matchmaking companies and theoretical perspectives on close relationships suggest that initial attraction is, to some extent, a product of two people'...

Clopidogrel-Induced Insulin Autoimmune Syndrome: A Newly Recognized Cause of Hypoglycemia in a Patient Without Diabetes.

Insulin autoimmune syndrome (IAS), defined as hyperinsulinemic hypoglycemia with high titers of anti-insulin antibodies, is frequently reported in Jap...

A Machine Learning Approach Using Survival Statistics to Predict Graft Survival in Kidney Transplant Recipients: A Multicenter Cohort Study.

Accurate prediction of graft survival after kidney transplant is limited by the complexity and heterogeneity of risk factors influencing allograft sur...

Quantitative Testing of fMRI-Compatibility of an Electrically Active Mechatronic Device for Robot-Assisted Sensorimotor Protocols.

OBJECTIVE: To develop a quantitative set of methods for testing the functional magnetic resonance imaging (fMRI) compatibility of an electrically-acti...

An Ameliorated Prediction of Drug-Target Interactions Based on Multi-Scale Discrete Wavelet Transform and Network Features.

The prediction of drug-target interactions (DTIs) via computational technology plays a crucial role in reducing the experimental cost. A variety of st...

An efficient method for kidney allocation problem: a credibility-based fuzzy common weights data envelopment analysis approach.

Given the perennial imbalance and chronic scarcity between the demand for and supply of available organs, organ allocation is one of the most critical...

Anatomic and non-anatomic anterior cruciate ligament posterolateral bundle augmentation affects graft function.

PURPOSE: The purpose of this study is to compare knee laxity and graft function (tissue force) between anatomic and non-anatomic posterolateral (PL) b...

In silico identification of milk antihypertensive di- and tripeptides involved in angiotensin I-converting enzyme inhibitory activity.

Identification of bioactive milk peptides could improve food technology through improved selection of food supplements with a focus on antihypertensiv...

Research on Safety and Compliance of a New Lower Limb Rehabilitation Robot.

The lower limb rehabilitation robot is an application of robotic technology for stroke people with lower limb disabilities. A new applicable and effec...