Latest AI and machine learning research in transplantation for healthcare professionals.
BACKGROUND AND PURPOSE: A single, oral dose of 3 mg/day tacrolimus, approved for myasthenia gravis (MG) treatment in Japan, was shown to reduce steroid dose and anti-acetylcholine receptor (AChR) antibody titers as well as to improve MG symptoms. However, no studies have investigated the association between tacrolimus concentration and its clinical efficacy in MG. In this study, we aimed to determ...
BACKGROUND AND OBJECTIVE: Immunosuppression therapy following lung transplantation fails to prevent chronic rejection in many patients, which is associated with lack of suppression of cytotoxic mediators and pro-inflammatory cytokines in peripheral blood T and natural killer T (NKT)-like cells. Histone acetyltransferases (HATs) and histone deacetylases (HDACs) upregulate/downregulate pro-inflammat...
Machine learning methods provide a powerful approach for analyzing longitudinal data in which repeated measurements are observed for a subject over ti...
Autogenous bone grafts are the gold standard for reconstruction of atrophic jaws, pseudoarthroses, alveolar clefts, orthognathic surgery, mandibular d...
BACKGROUND: Infections caused by antimicrobial-resistant bacteria are associated with increased mortality and health care costs. Enterococci have been...
INTRODUCTION: Since directly acting antivirals (DAAs) for treatment of hepatitis C virus (HCV) were introduced, conflicting data emerged about the ris...
Three new D-A-π-A metal-free organic dyes based on phenothiazine as a donor (D) and non-conjugated π-spacer were designed and synthesized. The incorpo...
BACKGROUND: Kidney donor outcomes are gaining attention, particularly as donor eligibility criteria continue to expand. Kidney size, a useful predicto...
Identifying novel biomarkers to predict renal graft survival is important in post-transplant clinical practice. Serum creatinine, currently the most p...
Quantitative structure activity relationships (QSARs) are theoretical models that relate a quantitative measure of chemical structure to a physical pr...
PURPOSE: Segmentation of the liver from abdominal computed tomography (CT) images is an essential step in some computer-assisted clinical intervention...
The level of fibroblast growth factor 23 (FGF23) may be considered as a prognostic factor for assessing renal function in regulating components of ph...
Series elastic actuation that takes inspiration from biological muscle-tendon units has been extensively studied and used to address the challenges (e...
Embedding cost-sensitive factors into the classifiers increases the classification stability and reduces the classification costs for classifying high...
Retrograde perigraft access to the aneurysmal sac for type 2 endoleak embolization is a relevant alternative to standard transarterial and translumbar...
Cyclophosphamide (CP) is a widely used cytotoxic alkylating agent with antitumor and immunosuppressant properties that is associated with various form...
BACKGROUND: The IGAR (Image-guided Automated Robot) is a robotic platform capable of performing highly accurate clinical interventions under image gui...
Tacrolimus is a potent immunosuppressant; however, it suffers from several problems such as poor water solubility (4-12 μg/mL), low and variable oral ...
Due to increasing reports on poor-quality palm oil in the market, there has been a continual decrease in demand and revenue cum product rejection of p...
To ensure the correctness of network analysis methods, the network (as the input) has to be a sufficiently accurate representation of the underlying d...