Latest AI and machine learning research in transplantation for healthcare professionals.
Progressive supranuclear palsy (PSP) is a neurodegenerative 4R tauopathy clinically presenting with atypical parkinsonism or cognitive behavioral changes and a relatively uniform neuropathology. We recently identified rare HLA haplotypes in PSP and now examine whether HLA haplotypes are associated with different cytopathological and clinical phenotypes. Retrospective collection of clinical data an...
Patients with myelodysplastic syndromes (MDS) exhibit diverse disease trajectories necessitating different clinical approaches ranging from watch-and-wait strategies to hematopoietic stem cell transplantation. Existing risk scores like the IPSS-R or EASIX provide static risk stratification at diagnosis but do not capture evolving disease dynamics. We address this problem by introducing a dynamic, ...
Understanding gene-disease associations is important for uncovering pathological mechanisms and identifying potential therapeutic targets. Knowledge g...
Are large language models robust against adversarial attacks in medical peer review? In this factorial experimental study, invisible text injection at...
The dire consequences of heart failure (HF) patient non-response to guideline directed medical therapy often fuel early, non-selective referral for su...
White matter hyperintensities (WMH) are frequently observed on MRI in aging and Alzheimer’s disease (AD), yet their microstructural pathology remains ...
Heart failure is a major cause of morbitidy and mortality, with the severest forms requiring heart transplantation. Heart size matching between the do...
Chronic kidney disease (CKD) affects millions worldwide and often progresses to end-stage renal disease (ESRD), for which kidney transplantation remai...
To identify post-marketing adverse event (AE) signals associated with isotretinoin using real-world data from the U.S. Food and Drug Administration (F...
Disease heterogeneity and commonality pose significant challenges to precision medicine, as traditional approaches frequently focus on single disease ...
Cardiac allograft rejection (CAR) remains the leading cause of early graft failure after heart transplantation (HT). Current diagnostics, including hi...
Accurate intraoperative assessment of macrovesicular steatosis in donor liver biopsies is critical for transplantation decisions but is often limited ...
Spinal cord injury (SCI) remains a devastating neurological condition with high global incidence and minimal curative options. The pathobiology is mul...
Coronary artery disease (CAD) is the leading cause of death worldwide, yet it is highly preventable. Early detection is critical, particularly because...
Forecasting acute organ injury trajectory remains a critical clinical challenge. Current approaches rely on serial measurements, delaying decision-mak...
Lung transplantation remains the only definitive treatment for patients with end-stage respiratory failure; however, it is burdened by a substantial r...
Although living donor kidney transplantation (LDKT) generally achieves excellent outcomes, 5–12% of recipients experience early graft dysfunction, whi...
Assessment of interstitial fibrosis is essential in the diagnosis and prognosis of kidney diseases. However, current histologic scoring methods using ...
Surgical pathology reports provide essential diagnostic information critical for cancer staging, treatment planning, and cancer registry documentation...
Accurate early prediction of neurological outcomes in comatose patients after cardiac arrest is critical for guiding therapeutic decisions and improvi...