Transplantation

Latest AI and machine learning research in transplantation for healthcare professionals.

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Automated evaluation with deep learning of total interstitial inflammation and peritubular capillaritis on kidney biopsies.

BACKGROUND: Interstitial inflammation and peritubular capillaritis are observed in many diseases on native and transplant kidney biopsies. A precise and automated evaluation of these histological criteria could help stratify patients' kidney prognoses and facilitate therapeutic management.

Nov 30 2023 37197910

Unsupervised and supervised AI on molecular dynamics simulations reveals complex characteristics of HLA-A2-peptide immunogenicity.

Immunologic recognition of peptide antigens bound to class I major histocompatibility complex (MHC) molecules is essential to both novel immunotherapeutic development and human health at large. Current methods for predicting antigen peptide immunogenicity rely primarily on simple sequence representations, which allow for some understanding of immunogenic features but provide inadequate considerati...

Nov 22 2023 38233090
Advancing clinical translation of cardiac biomechanics models: a comprehensive review, applications and future pathways.

Cardiac mechanics models are developed to represent a high level of detail, including refined anatomies, accurate cell mechanics models, and platforms...

Nov 14 2023 38500690
Efficacy of Pulse Methylprednisolone in Treatment of Acute Respiratory Distress Syndrome due to Malaria: A Randomized Controlled Clinical Trial.

: To study the efficacy of pulse methylprednisolone (MPS) therapy in patients with malaria-associated acute respiratory distress syndrome (ARDS). : Th...

Nov 1 2023 38720494
The Role of Vitamin D Binding Protein and Vitamin D Level in Mortality of Sepsis Patients.

BACKGROUND: Vitamin D plays crucial roles in immune cell function, including macrophage activation, immune response modulation, and antimicrobial pept...

Oct 1 2023 38618268
[Robot-assisted left-side partial nephrectomy with a segmental resection of left lower ureter and Boari reconstruction].

Renal cell carcinoma (RCC) accounts for more than 90% of cases of malignant kidney tumors and represents 2-3% of all malignancies worldwide. Clear cel...

Sep 1 2023 37850292
DETERMINATION OF THE PRA POSITIVITY PERCENTAGE IN MALE PATIENTS WITH CHRONIC KIDNEY DISEASE BY USING FLOW CYTOMETRY TECHNIQUE.

The antibodies directed against human leukocyte antigen (HLA) molecules, which play a crucial role in allograft histocompatibility, are called anti-HL...

Aug 1 2023 38549598
Toward a general neural network force field for protein simulations: Refining the intramolecular interaction in protein.

Molecular dynamics (MD) is an extremely powerful, highly effective, and widely used approach to understanding the nature of chemical processes in atom...

Jul 14 2023 37431910
[Experience in performing robot-assisted radical prostatectomy in patients after heart transplan- tation].

INTRODUCTION: Prostate cancer (PCa) occupies a leading position in the structure of oncological morbidity and mortality and is an urgent problem of mo...

Jul 1 2023 37417416
Clinical efficacy of modified sacral fixation under Leonardo da Vinci robot laparoscopy for pelvic organ prolapse.

OBJECTIVE: The aim of this study was to analyze the clinical efficacy of modified sacral fixation under Leonardo da Vinci robot laparoscopy for pelvic...

Jul 1 2023 37458627
Artificial intelligence, machine learning, and deep learning in liver transplantation.

Liver transplantation (LT) is a life-saving treatment for individuals with end-stage liver disease. The management of LT recipients is complex, predom...

Jun 1 2023 37208107
[Research on Life Cycle Management of Medical Consumables Based on Hospital Resource Planning System].

OBJECTIVE: In order to improve the compatibility of the hospital resource planning (HRP) system for the whole life cycle of medical consumables, and t...

May 30 2023 37288643
Deep Learning Using Preoperative AS-OCT Predicts Graft Detachment in DMEK.

PURPOSE: To evaluate a novel deep learning algorithm to distinguish between eyes that may or may not have a graft detachment based on pre-Descemet mem...

May 1 2023 37184500
Chylous Ascites After Robot-Assisted Laparoscopic Donor Nephrectomy: Is Early Surgical Intervention Necessary?

OBJECTIVES: Chylous ascites is a rare complication that may occur after living donor nephrectomy. The continuous loss of lymphatics, which carries a h...

May 1 2023 37334687
Integration of deep learning-based histopathology and transcriptomics reveals key genes associated with fibrogenesis in patients with advanced NASH.

Nonalcoholic steatohepatitis (NASH) is the most common chronic liver disease globally and a leading cause for liver transplantation in the US. Its pat...

Apr 18 2023 37075704
Biomarkers of aging - current state of knowledge.

Aging is a process of gradual decline in the functional capacity of the human body that leads to a significant increase in the risk of death over time...

Jan 1 2023 37923561
How Brain Organoids Are Revolutionizing Neuroscience.

Measuring just a millimeter or two in diameter, brain organoids are a far cry from a fully functioning human brain. But these miniature tissues, typic...

Jan 1 2023 37607158
Differential Expression, Functional and Machine Learning Analysis of High-Throughput -Omics Data Using Open-Source Tools.

Today, -omics analyses, including the systematic cataloging of messenger RNA and microRNA sequences or DNA methylation patterns in a cell population, ...

Jan 1 2023 36418696
Deep Learning on Chromatin Accessibility.

DNA accessibility has been a powerful tool in locating active regulatory elements in a cell type, but dissecting the combinatorial logic within these ...

Jan 1 2023 36807077
Clinical Importance of 3D Volography in Breast Imaging.

The clinical applications of the volography algorithm and concomitant refraction-corrected reflection algorithm as described in Chap. 10 are discussed...

Jan 1 2023 37495921
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