Latest AI and machine learning research in transplantation for healthcare professionals.
The cancer-testis antigen MAGE-A4 is an attractive immunotherapy target due to its high expression in various malignancies and restricted expression in normal tissues. Peptides derived from intracellular MAGE-A4 are presented on the cell surface by HLA-A*02:01, enabling targeting by T-cell receptor (TCR)-like molecules. We identified a TCR-like antibody recognizing the HLA-A *02:01-presented MAGE-...
Smartphone-based fundus imaging (SBFI) is an emerging approach with potential relevance for global ophthalmic care, including in low- and middle-income countries and other resource-constrained settings. This scoping review, based on a structured literature search, synthesises current SBFI technology, clinical and teaching applications, implementation challenges and future directions. Analysing 30 ...
Oral squamous cell carcinoma (OSCC) continues to be associated with a poor prognosis despite recent advances in surgical and adjuvant treatment. Altho...
Immunological biomarkers are increasingly relevant for personalized cancer treatment, but peripheral blood-derived biomarkers are not yet used to guid...
Personalized neoantigen cancer vaccine is a promising strategy for precision immunotherapy by targeting patient-specific and mutation-derived tumor an...
Water scarcity has intensified interest in passive, sorption-based atmospheric water harvesting (SAWH), interfacial evaporation (IE), and radiative co...
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a curative treatment option for a significant proportion of patients with acute myel...
BACKGROUND: Sepsis-associated acute kidney injury (SA-AKI) is a frequent and high-mortality complication in critically ill patients. Current diagnosti...
Microphysiological immune-on-chip systems have emerged as transformative biomedical microdevices capable of recreating the structural, biochemical, an...
INTRODUCTION: Chronic kidney disease (CKD) disproportionately burdens non-Hispanic Black (NHB) patients who experience a three- to four-fold higher ri...
BACKGROUND: To compare machine learning (ML) performance for detecting visual field (VF) progression across different labeling strategies using a larg...
Nanomaterial-based drug delivery systems (NDDS) have become enabling technologies for small-molecule reformulation, RNA medicines, vaccines, gene edit...
Musculoskeletal (MSK) disorders remain a leading cause of disability, yet effective disease-modifying therapies are limited by poor translational rele...
BACKGROUND: Anorexia nervosa (AN) is frequently accompanied by metabolic disturbances and immune dysregulation, yet its peripheral molecular mechanism...
Humans think and act not only with the brain but also with the heart, lungs, gut, and other viscera, such as the bladder, long regarded as primarily v...
The adaptive immune receptor repertoire (AIRR) - the collection of an individual's B-cell and T-cell receptors (BCRs and TCRs, respectively) - encodes...
Current vascular grafts face limitations including inadequate mechanical strength, inability to replicate small and complex anatomical structures, eth...
Driven by technological advancements, donor shortages, and an aging population, utilization of left ventricular assist devices (LVAD), both as a bridg...
BACKGROUND: Cardiovascular events are a leading cause of mortality after liver transplantation (LT), and existing risk scores incompletely capture myo...
The surgical bone drilling process is unavoidable in orthopedic, traumatological and dental applications for screw, plate and implant placement proced...