Transplantation

Latest AI and machine learning research in transplantation for healthcare professionals.

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Copper transporters promote the malignant progression of glioblastoma by regulating the immunosuppressive tumour microenvironment via the SLC31A1-WNT5A axis.

BACKGROUND: The prognosis for patients with glioblastoma (GBM) remains extremely poor, a challenge largely attributable to the complex nature of its malignant progression and an insufficient understanding of the dynamic plasticity and spatial heterogeneity inherent in the tumour microenvironment during invasion. In recent years, copper has emerged as a trace element of considerable interest due to...

May 12 2026 42121271

Predicting biliary complications after liver transplantation: a machine learning and nomogram-based exploratory study.

BACKGROUND: Accurate risk stratification of biliary complications (BCs) after liver transplantation (LT) remains challenging. This study aimed to develop and validate a machine learning (ML) and nomogram framework comprising a ML-based web calculator and a clinically interpretable nomogram for post-LT BCs. METHODS: This retrospective study analyzed 133 LT patients (2011-2025), randomly split into ...

May 12 2026 42115961
PolyGraph - Flexible, Biocompatible & Electrically Optimized Graphene-Polymer Composites for Next-Generation Neural Interfaces.

Neural interfacing materials must deliver exceptional electrochemical performance, while integrating safely with the central nervous system. In this s...

May 12 2026 42117387
Explainable retinal deep learning for cardiovascular risk stratification: a multiple modality analysis framework with vascular-centric interpretability and robustness.

Early non-invasive prediction of cardiovascular risk is an essential prerequisite for preventive medicine, especially in resource-limited settings. Re...

May 11 2026 42115996
Involved nodal versus elective neck radiotherapy (INVERT) for head and neck squamous cell carcinoma: a prospective phase II randomized controlled trial protocol.

BACKGROUND: Definitive chemoradiotherapy for head and neck squamous cell carcinomas (HNSCC) carries significant long-term toxicities, with elective ne...

May 11 2026 42116021
A machine learning-based megakaryocyte identification system uncovers resident organs, markers, and functional diversity.

The organ- and stage-specific diversity of megakaryocytes (MKs) has prompted a reassessment of their distribution and functions. By integrating single...

May 11 2026 42119559
Screening of Sepsis Diagnostic Biomarkers Based on Fumarate Metabolism-Related Genes with Analysis of Immune Infiltration and Subtype Identification.

BACKGROUND: Sepsis is a major global health challenge characterized by a complex pathogenesis involving an early hyperinflammatory phase followed by a...

May 11 2026 42109201
Assessing the Reliability of MRI and CT Scans for Liver Volume Estimation in Patients Undergoing Liver Transplantation.

OBJECTIVE: Magnetic resonance imaging (MRI) and computed tomography (CT) are commonly used to measure organ volumes, but accuracy has not been methodi...

May 11 2026 42112599
Wake-Up-Free Complementary Metal-Oxide-Semiconductor-Compatible Multiferroic Heterostructures for Application in Magnetoelectric Spin-Orbit Devices.

The integration of multiferroic materials into complementary metal-oxide-semiconductor (CMOS) technology presents an exciting frontier in nanoelectron...

May 11 2026 42113114
Molecular mechanisms linking cadmium chloride exposure to ankylosing spondylitis: an integrative network-based study.

Chronic cadmium chloride (CC) exposure is associated with diverse toxicological outcomes, yet its potential role in the pathogenesis of ankylosing spo...

May 11 2026 42113191
Characterization of telomere-related gene subtypes in lung adenocarcinoma and their implications for prognosis and treatment.

BACKGROUND: Telomeres, located at chromosome ends, regulate cell division and maintain genomic stability. Telomere-related genes (TRGs) play essential...

May 11 2026 42113288
Implementation of artificial intelligence to automate physical disector in a fractionator design for quantification of stem cell-derived neurons.

Accurate quantification of stem cell-derived dopaminergic neurons is essential for advancing cell therapy strategies in Parkinson's disease (PD). Trad...

May 9 2026 42107341
Single-cell profiling identifies a pro-tumoral VCAN positive macrophage subset and defines a prognostic signature in glioblastoma.

Glioblastoma (GBM), the most aggressive primary brain tumor, develops within a tumor microenvironment (TME) dominated by tumor-associated macrophages ...

May 9 2026 42105040
Integrating machine learning and single-cell sequencing to reveal the role of kinase-related genes in subtype classification and prognostic significance of lung squamous cell carcinoma.

BACKGROUND: Lung squamous cell carcinoma (LUSC) exhibits poor prognosis and a highly complex tumor immune microenvironment (TIME), creating an urgent ...

May 9 2026 42105179
A national-scale sandy beach dataset for India derived from high-resolution satellite imagery and deep learning.

Sandy beaches are important coastal features with ecological, social, and economic significance, yet comprehensive national-scale datasets mapping the...

May 9 2026 42106382
Integrative analysis of single-cell and transcriptomic data with RT-qPCR validation explores TRPM4-associated gene signatures in osteoarthritis synovium.

Osteoarthritis (OA) is a chronic, disabling condition whose pathogenesis remains unclear. TRPM4 is closely associated with OA, but its specific roles ...

May 9 2026 42106542
A fully automated framework for acoustic identification and localization of terrestrial wildlife at scale.

Autonomous acoustic recorders are increasingly important tools for monitoring sound-producing taxa. Coupled with advances in machine learning, they en...

May 9 2026 42106579
Cross-Species Plant Single-Cell Analysis: Community Challenges and Shared Solutions.

Single-cell genomics is rapidly reshaping plant biology, yet broader adoption is limited by plant-specific technical constraints, fragmented tools, an...

May 8 2026 42099283
Electrochemical Biosensors for Hepatocellular Carcinoma: Advances, Analytical Performance, and Clinical Translation.

Hepatocellular carcinoma (HCC) remains a leading cause of cancer-related mortality worldwide due to the limited sensitivity of current surveillance an...

May 8 2026 42100893
Managing multidrug resistant Gram-negative bacteraemia in immunocompromised hosts.

PURPOSE OF REVIEW: Multidrug-resistant Gram-negative bloodstream infections (MDR-GNBSI) are increasingly frequent in immunocompromised hosts, particul...

May 7 2026 42107119
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