Latest AI and machine learning research in transplantation for healthcare professionals.
Type 1 diabetes (T1D) is a T cell-mediated disease with a strong immunogenetic human leukocyte antigen (HLA) dependence. HLA allelic influence on the T cell receptor (TCR) repertoire shapes thymic selection and controls activation of diabetogenic clones yet remains largely unresolved in T1D. We sequenced the circulating TCRĪ² chain repertoire from 2250 HLA-typed participants across three cross-sect...
BACKGROUND: Heart failure mortality has risen sharply after years of decline, highlighting the limitations of current risk assessment tools in accuracy, complexity, and cost, and the need for improved predictive models. To address this gap, we developed and validated a deep learning model to improve short-term mortality prediction in heart failure patients. METHODS: In this retrospective study, we...
Ulcerative colitis (UC) represents a chronic, relapsing inflammatory condition primarily affecting the colonic and rectal mucosa, presenting substanti...
Out-of-distribution (OOD) detection has emerged as a crucial safeguard for ensuring trustworthy deployment of machine learning models in safety-critic...
BACKGROUND: This study aimed to assess the value of blood plasma autofluorescence spectroscopy in classifying renal injury after renal transplantation...
The advancement of robotic fish necessitates examination of whether caudal fins should be specifically designed for individual body shapes or if gener...
Neuromorphic Computing (NC) is a promising candidate for Artificial Intelligence (AI) applications. To realize NC, electronic analogues of brain compo...
BACKGROUND: The COVID-19 pandemic offers a powerful opportunity to develop methods for monitoring the spread of infectious diseases based on their sig...
Optimizing organic photovoltaic (OPV) performance requires navigating the high-dimensional, interdependent processing parameters governing bulk hetero...
The genetic mechanisms of ~90% of Alzheimer's disease (AD)-associated variants residing in noncoding DNA remain poorly understood. To address this, we...
RATIONALE AND OBJECTIVES: Accurate staging of hepatic fibrosis is essential for guiding immunosuppressive and antifibrotic therapies. However, percuta...
UNLABELLED: Early identification of patients at high risk for multidrug-resistant organism (MDRO) infection in catheter-related bloodstream infection ...
BACKGROUND: Peer review remains central to ensuring research quality, yet it is constrained by reviewer fatigue and human bias. The rapid rise in scie...
BACKGROUND: Delirium is a frequent postoperative complication among patients who have undergone cardiac surgery and is associated with prolonged hospi...
BACKGROUND: Lung adenocarcinoma (LUAD) is a major lung cancer subtype influenced by environmental factors. Benzo[a]anthracene (BaA), a common Group 2B...
BACKGROUND: Mitochondrial dysfunction contributes to the pathogenesis of multiple diseases. This study explores the involvement of mitochondrial dysfu...
PURPOSE: Low-grade gliomas(LGGs) show significant clinical and molecular heterogeneity, complicating progression prediction with conventional indicato...
Light-sheet fluorescence microscopy (LSFM) has emerged as a revolutionary imaging modality for investigating intact three-dimensional brain structures...
The occurrence and development of a wide range of preeclampsia (PE), especially early-onset preeclampsia (EOPE), is closely associated with the immune...