Transplantation

Latest AI and machine learning research in transplantation for healthcare professionals.

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Fundamentals of big data and artificial intelligence in transfusion medicine.

Within the digital transformation of medicine, transfusion medicine has quietly become a big-data discipline. The long-standing tradition of blood product standardization (e.g., ISBT-128) and large donor cohorts being followed over years-some of which are sampled in national biobank projects, build a favourable setting. In parallel, recent advances in artificial intelligence (AI) and data integrat...

Mar 23 2026 41871959

Integrative machine learning analysis suggests novel molecular targets for liver cancer diagnosis and therapy.

BACKGROUND: Hepatocellular carcinoma (HCC) is a critical condition characterized by unchecked cellular growth in the liver, often leading to systemic inflammation and organ failure. Although its complex molecular mechanisms are not fully understood, the primary aim of this study is to enhance the timely and effective diagnosis and treatment of HCC by identifying key molecular targets and pathways....

Mar 22 2026 41866435
Harnessing big data and artificial intelligence in transfusion medicine: Opportunities for precision, safety and efficiency.

Transfusion medicine generates enormous volumes of data across the vein-to-vein continuum, spanning donor characteristics, laboratory testing, compone...

Mar 22 2026 41866232
Precision oncology meets nanotechnology: AI-driven liposomal nanocarriers for enhanced cancer immunotherapy.

The integration of artificial intelligence (AI) with nanotechnology is redefining therapeutic strategies in cancer immunotherapy and chemotherapy. The...

Mar 21 2026 41871725
LLM-guided population-based reinforcement learning: A scalable methodology for adaptive hyperparameter optimization.

Population-Based Training (PBT) has the drawback of using fixed, pre-programmed mutation and selection rules to optimize hyperparameters, which are no...

Mar 21 2026 41953897
Integrated single-cell and bulk transcriptomics reveals STAB1 as a novel therapeutic target for ovarian cancer.

The immunosuppressive tumor microenvironment (TME) and intrinsic heterogeneity of ovarian cancer (OC) are primary drivers of therapeutic resistance an...

Mar 21 2026 41865597
Attitudes toward artificial intelligence among individuals with anxiety, depression, bipolar disorders, and schizophrenia.

BACKGROUND: Artificial intelligence (AI) increasingly supports medical diagnosis, interventions, and clinical decision-making. In various domains of h...

Mar 20 2026 41921249
Backpropagation-free spiking neural networks with the forward-forward algorithm.

Spiking Neural Networks (SNNs) offer a biologically inspired computational paradigm that emulates neuronal activity through discrete spike-based proce...

Mar 20 2026 41862583
Development of comparative and machine learning-based methodologies for the identification of inks applicable in the field of cultural heritage and forensic science.

This study proposes the development of comparative and machine learning-based methodologies for the identification of inks and pigments, with potentia...

Mar 19 2026 41863927
HueTools: A modular image processing and ML toolkit for quantitative colorimetric assay development.

Colorimetric assays offer a low-cost, accessible means of diagnostic testing but often suffer from subjective interpretation and variability caused by...

Mar 19 2026 41864342
Real-world unified denoising for multi-organ fast MRI: a large-scale prospective validation.

Lengthy acquisition time remains a key bottleneck for the widespread use of MRI in clinics. While accelerated MRI can reduce scan duration, it often i...

Mar 19 2026 41857225
Wavelet-Transformed Frequency Linked Attention with Selective Hierarchy for Abdominal Organ Segmentation.

The clinical use of computed tomography (CT) scans has been steadily rising due to their ability to provide detailed three-dimensional (3D) representa...

Mar 19 2026 41857235
Soft Robotics and Advanced Technologies for Minimally Invasive Bioprinting: The Future of Internal Organ Repair.

Bioprinting, first proposed in the 1980s for ex vivo tissue fabrication, has evolved into a cornerstone of regenerative medicine. Conventional approac...

Mar 19 2026 41852289
MOTDNet: Multi organ task decoupling network for cell segmentation.

In histopathology, cell detection and segmentation of Hematoxylin and Eosin (H&E) stained tissue images are essential clinical tasks. Existing methods...

Mar 18 2026 41921258
Artificial intelligence-guided design of LNPs for in vivo targeted mRNA delivery via analysis of the spatial conformation of ionizable lipids.

Efficient mRNA delivery to specific tissues requires optimized ionizable lipids, yet the role of lipid spatial conformation in organ targeting and end...

Mar 18 2026 41851281
Thymic health and immunotherapy outcomes in patients with cancer.

Although immunotherapy has revolutionized cancer treatment, many patients still experience limited benefit, highlighting the urgent need for improved ...

Mar 18 2026 41851467
The Burden, Outcomes, and Management of Patients with Aldosterone Dysregulation: A Targeted Literature Review.

INTRODUCTION: Aldosterone dysregulation (excess aldosterone production at the source within the adrenal glands) in the absence of primary aldosteronis...

Mar 18 2026 41849107
Application of machine learning in the research progress of post-kidney transplant rejection.

Post-kidney transplant rejection is a critical factor influencing transplant success rates and the survival of transplanted organs. With the rapid adv...

Mar 18 2026 41607813
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