Latest AI and machine learning research in transplantation for healthcare professionals.
BACKGROUND: Metabolic dysfunction-associated steatohepatitis (MASH) cirrhosis is a leading indication for liver transplantation (LT). Patients with MASH cirrhosis are complex and often have extensive comorbidities. The current model for end-stage liver disease (MELD)-based liver allocation system has suboptimal concordance in predicting waitlist mortality for patients with MASH cirrhosis. Furtherm...
Pathogenic mutations in Leucine-rich repeat kinase 2 (LRRK2) are the predominant genetic cause of Parkinson's disease (PD) and often increase kinase activity, making LRRK2 inhibitors promising treatment options. Although LRRK2 kinase inhibitors are advancing clinically, non-invasive readouts of LRRK2-linked pathway modulation remain limited. Profiling urinary proteomes from 1215 individuals across...
BACKGROUND: Epidermal growth factor (EGF) and its receptor EGF(EGFR) play crucial roles in glioblastoma (GBM) prognosis. However, non-invasive assessm...
Understanding and predicting catalyst performance from structural and electronic information remains a central challenge in organocatalysis. Here, we ...
Aging and age-related diseases are a major public health concern, driving interest in anti-aging research. While small molecules and natural compounds...
Immunotherapy, a therapeutic strategy aimed at modulating the host immune system, has undergone rapid evolution over recent decades, particularly in o...
ETHNOPHARMACOLOGICAL RELEVANCE: According to the Traditional Chinese Medicine (TCM) tenet that "internal imbalances manifest externally," skin aging r...
In the over-century-long history of colorectal tumor surgery, achieving organ function preservation has consistently been a central topic. Currently, ...
BACKGROUND: Endovascular aneurysm repair (EVAR) has become a standard treatment for abdominal aortic aneurysms. However, the evolution of EVAR researc...
Kidney transplantation significantly improves outcomes in end-stage renal disease, however, long-term graft survival remains suboptimal. Traditional p...
Learning under uncertainty has become increasingly critical in data-intensive artificial intelligence applications, requiring computing systems that u...
Lung cancer remains a significant global health challenge, with metastatic progression being the leading driver of mortality. Organoid technology prov...
PURPOSE: Some patients with drug-induced liver injury (DILI) would progress into chronicity or lethal. Although adipocyte fatty acid-binding protein (...
Understanding the behavioral and morphological dynamics of moving model organisms like the zebrafish larvae requires accurate, high-throughput 3D anal...
Chemical fingerprinting is a key environmental forensics technique used in oil spill investigations to identify the source and type of oil in spill re...
OBJECTIVES: Organ-on-a-chip (OoC), as a highly biomimetic microphysiological system, is demonstrating significant potential in oral medicine research ...
BACKGROUND AND PURPOSE: To extend the previously reported geometric analysis of HaN-Seg: The Head and Neck Organ-at-Risk CT and MR Segmentation Challe...
Organotypic retinal explant cultures are a valuable experimental tool for investigating neuroretinal diseases and advancing therapeutic strategies. Ex...
BACKGROUND: Survival outcomes in locally advanced gastric cancer remain heterogeneous despite standard treatment and outcome classifications. Visceral...