Transplantation

Latest AI and machine learning research in transplantation for healthcare professionals.

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Integrated multi-omics analysis of prognostic model and immune microenvironment in intrahepatic cholangiocarcinoma.

BACKGROUND: Intrahepatic cholangiocarcinoma (iCCA) is an aggressive malignancy originating from the epithelial lining of second-order bile ducts. Despite advances in immunotherapy, which underscore the pivotal roles of T-cell dynamics and tumor microenvironment (TME) remodeling in anti-tumor immunity, iCCA remains a clinical challenge due to its rapid progression. Consequently, there is a pressing...

Jan 19 2026 41558145

Smart Designer Nanozymes for Precision Cancer Therapy: Recent Advances and Prospects.

Nanozymes are enzyme-mimicking nanomaterials that are promising for diverse biomedical applications; they enable stable, tunable, and multifunctional cancer therapies via exploiting tumor microenvironment (TME) cues to regulate reactive oxygen species (ROS) and catalytic activities locally, aided by state-of-the-art fabrication methods and artificial intelligence (AI)-assisted designs. This review...

Jan 17 2026 41546641
Boosting angiogenesis experimentally in ovo by biofunctionalizing collagen membranes with platelet-rich fibrin and hyaluronic acid: implications for regenerative oral surgery?

PURPOSE: Biocompatible collagen membranes (CM) are widely used in regenerative dentistry, particularly in guided tissue regeneration (GTR) and guided ...

Jan 17 2026 41546800
Lactylation-driven gene signatures define breast cancer prognosis: a predictive model and insights into immune microenvironment dynamics.

BACKGROUND: Breast cancer is a leading cause of cancer-related mortality worldwide, with poor prognosis largely due to its invasive and metastatic nat...

Jan 17 2026 41547876
Gene Modification: Exploring the potential in treating kidney diseases.

Chronic kidney disease (CKD) is a leading cause of death worldwide. Currently available drugs slow but do not cure or prevent progression to end-stage...

Jan 17 2026 41554351
Towards open-set myoelectric gesture recognition via dual-perspective inconsistency learning.

BACKGROUND AND OBJECTIVE: Gesture recognition based on surface electromyography (sEMG) has achieved significant progress in human-machine interaction ...

Jan 16 2026 41576776
A Deep Learning Model for Dynamic Prediction of Acute Kidney Injury in Heart Failure Patientss.

BACKGROUND: This study aimed to develop and validate a dynamic prediction model for acute kidney injury (AKI) in heart failure (HF) patients. METHODS:...

Jan 16 2026 41548653
Diagnostic Accuracy of the National Library of Medicine (NLM) Screener Application in Screening for Malaria Parasites Among Blood Donors at the Korle-Bu Blood Bank, Ghana: A Cross-Sectional Study.

BACKGROUND AND AIMS: Malaria is a deadly disease spread through the bite of an infected female Anopheles mosquito and remains the leading cause of mor...

Jan 16 2026 41550292
Adaptive performance control of switched nonlinear systems under false data injection attacks and input saturation constraints.

Considering the controller-actuator channel subjected to false data injection (FDI) attacks, this study proposes an adaptive performance control strat...

Jan 15 2026 41548442
[Emphasizing evolution of key technological elements in reconstructive surgery].

Reconstructive surgery is fundamentally dedicated to restoring tissues and organs damaged by trauma, disease, or congenital anomalies, with the goal o...

Jan 15 2026 41539698
Predicting the Future Burden of Renal Replacement Therapy in Türkiye Using National Registry Data and Comparative Modeling Approaches.

BACKGROUND: Chronic kidney disease is a growing public health problem worldwide, and the number of patients requiring renal replacement therapy is ste...

Jan 15 2026 41540661
B-cell-directed Immunotherapy for Solid Tumors.

B-cell-directed immunotherapy holds great promise for treating solid tumors, where barriers such as desmoplastic stroma and low immunogenicity have li...

Jan 14 2026 41903994
Integrating CAR-T therapy with PD-1/PD-L1 blockade: Mechanisms, synergy, and optimized strategies in NSCLC.

Non-small cell lung cancer (NSCLC) presents persistent challenges in immunotherapy, as the clinical benefit of programmed cell death protein 1 (PD-1) ...

Jan 14 2026 41675056
Comprehensive review on immunotherapy for hepatocellular carcinoma: Current status and future perspectives.

Hepatocellular carcinoma (HCC), the most common form of primary liver cancer, remains a major global health concern due to its high incidence and mort...

Jan 14 2026 41532498
Robust Physics-Based Deep MRI Reconstruction via Diffusion Purification.

Deep learning (DL) supervised techniques have been extensively employed in magnetic resonance imaging (MRI) reconstruction, delivering notable perform...

Jan 14 2026 41533627
Nerves Stimulates Crosstalk between Gastric Cancer and Group 3 Innate Lymphoid Cells to Enhance Immunosuppression.

The immunosuppressive tumor microenvironment (TME) enables cancer cells to evade clinical immunotherapies. Neural networks are vital components of the...

Jan 14 2026 41534088
Transforming jet flavour tagging at ATLAS.

Jet flavour tagging enables the identification of jets originating from heavy-flavour quarks in proton-proton collisions at the Large Hadron Collider,...

Jan 14 2026 41535252
Computational frameworks for enhanced extracellular vesicle biomarker discovery.

Extracellular vesicles (EVs) are emerging as promising noninvasive biomarkers, yet their clinical translation faces substantial hurdles, primarily due...

Jan 14 2026 41535547
Identification of modifiable plasma protein markers of cardiometabolic risk in children and adolescents with obesity.

Pediatric obesity is linked to multi-organ inflammation and an increased risk of cardiometabolic and steatotic liver disease. To identify circulating ...

Jan 14 2026 41535681
Next-generation lung-cancer-on-a-chip: toward personalized therapy, AI, and CRISPR-driven models.

Lung-cancer-on-a-chip (LCOC) technologies have advanced rapidly, yet most models evaluate mechanical strain, patient-derived tumors, multi-organ inter...

Jan 14 2026 41544897
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