Universal precautions

Donor hepatitis C status is not associated with an increased risk of acute rejection in kidney transplantation.

INTRODUCTION: In renal transplantation, donor hepatitis C virus (HCV) status is crucial to consider when selecting a recipient given the high likelihood of transmission. We analyzed the effect of donor HCV status on post-renal transplant rejection and virologic infectious outcomes using electronic health record data from multiple US health care organizations.

Mesophilic Argonaute-Mediated Polydisperse Droplet Biosensor for Amplification-Free, One-Pot, and Multiplexed Nucleic Acid Detection Using Deep Learning.

Detection of nucleic acids from a single multiplexed and amplification-free test is critical for ensuring food safety, clinical diagnostics, and environmental monitoring. In this study, we introduced a mesophilic Argonaute protein from (CbAgo), which exhibits nucleic acid endonuclease activity, to achieve a programmable, amplification-free system (PASS) for rapid nucleic acid quantification at am...

Comparison between a deep-learning and a pixel-based approach for the automated quantification of HIV target cells in foreskin tissue.

The availability of target cells expressing the HIV receptors CD4 and CCR5 in genital tissue is a critical determinant of HIV susceptibility during se...

Machine Learning Bolsters Evidence That D1, Nef, and Tat Influence HIV Reservoir Dynamics.

BACKGROUND: The primary hurdle to curing HIV is due to the establishment of a reservoir early in infection. In an effort to find new treatment strateg...

Novel graph-based machine-learning technique for viral infectious diseases: application to influenza and hepatitis diseases.

BACKGROUND: Most infectious diseases are caused by viruses, fungi, bacteria and parasites. Their ability to easily infect humans and trigger large-sca...

From Skin Movement to Wearable Robotics: The Case of Robotic Gloves.

Previous research on wearable robotics focused on developing actuation mechanisms while overlooking influences of skin movement. During finger flexion...

Coordinating virus research: The Virus Infectious Disease Ontology.

The COVID-19 pandemic prompted immense work on the investigation of the SARS-CoV-2 virus. Rapid, accurate, and consistent interpretation of generated ...

Enriching Data Science and Health Care Education: Application and Impact of Synthetic Data Sets Through the Health Gym Project.

Large-scale medical data sets are vital for hands-on education in health data science but are often inaccessible due to privacy concerns. Addressing t...

Comparison of hepatitis B and SARS-CoV2 vaccination rates in people who attended Drugs and Addiction Centres.

BACKGROUND AND AIMS: Persons with substance use disorder are at increased risk for hepatitis B virus (HBV) infection. Although most of them are attach...

Clinical cure induced by pegylated interferon α-2b in the advantaged population of chronic hepatitis B virus infection: a retrospective cohort study.

BACKGROUND: Among the advantaged population with clinical cure of chronic hepatitis B, chronic inactive hepatitis B virus carriers (IHCs) and nucleosi...

Antifungal activity of eumelanin-inspired indoylenepheyleneethynylene against .

is an opportunistic fungal pathogen that causes meningitis in >152,000 immunocompromised individuals annually, leading to 112,000 yearly deaths. The ...

characterization and molecular epidemiology of spp. isolates from non-HIV patients in Guangdong, China.

BACKGROUND: The burden of cryptococcosis in mainland China is enormous. However, the characterization and molecular epidemiology in Guangdong, a key ...

Individual honey bee tracking in a beehive environment using deep learning and Kalman filter.

The honey bee is the most essential pollinator and a key contributor to the natural ecosystem. There are numerous ways for thousands of bees in a hive...

Combining Digital and Molecular Approaches Using Health and Alternate Data Sources in a Next-Generation Surveillance System for Anticipating Outbreaks of Pandemic Potential.

Globally, millions of lives are impacted every year by infectious diseases outbreaks. Comprehensive and innovative surveillance strategies aiming at e...

Impacts of ainuovirine-based and efavirenz-based antiretroviral therapies on the lipid profile of HIV/AIDS patients in southern China: a real-world study.

BACKGROUND: The newly approved third-generation oral anti-HIV-1 drug, ainuovirine (ANV), was used in combination with nucleoside reverse transcriptase...

antibacterial activity of antiretroviral drugs on key commensal bacteria from the human microbiota.

INTRODUCTION: Antiretroviral therapy has improved life expectancy in HIV-infected patients. However, people living with HIV under antiretroviral thera...

Development and application of an indirect ELISA and nested PCR for the epidemiological analysis of among pigs in China.

INTRODUCTION: () is an important opportunistic and zoonotic pathogen which is associated with many diseases in humans and animals. However, the patho...

Cases of Monkeypox show highly-overlapping co-infection with HIV and syphilis.

PURPOSE: Ongoing Monkeypox (MPX) outbreaks in countries outside Africa have unique characteristics. However, data on cohorts of confirmed cases in Chi...

Supervised machine learning algorithms to predict the duration and risk of long-term hospitalization in HIV-infected individuals: a retrospective study.

OBJECTIVE: The study aimed to use supervised machine learning models to predict the length and risk of prolonged hospitalization in PLWHs to help phys...

The antibacterial activity of berberine against : its therapeutic potential in inflammatory acne.

() is a major pathogen implicated in the evolution of acne inflammation. Inhibition of -induced inflammation is a prospective acne therapy strategy. ...