Urology

Latest AI and machine learning research in urology for healthcare professionals.

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Enhancing Model Generalizability in Medical Artificial Intelligence: Systematic Comparison of Categorical Encoding and Sampling Techniques for Imbalanced Data.

BACKGROUND: Despite the increasing use of machine learning (ML) in clinical research, the early stages of data preparation, especially for structured clinical data, often receive limited methodological scrutiny. These datasets typically contain missing values, complex categorical variables, and imbalanced class distributions, all of which complicate downstream model development and interpretation....

Apr 13 2026 41973872

Development and Validation of a Web Calculator for Predicting the Risk of Lower Limb Varicose Veins.

The aims of the present study were to develop and validate a predictive model for lower limb Varicose Veins, and to visualize the results using a web calculator for assessing the probability of patients developing Lower Limb Varicose Veins. A convenience sampling method was employed to select 421 patients from December 2023 to April 2024 at the health check-up center and vascular surgery outpatien...

Apr 13 2026 41974098
Using causal machine learning and real world data to improve dose response decision making for secukinumab in psoriatic arthritis.

Personalized treatment in psoriatic arthritis (PsA) remains challenging, particularly in guiding dose escalation decisions. We applied a causal machin...

Apr 11 2026 41965445
Feasibility of using geometry-based synthetic dose distributions for Knowledge-based planning model training.

BACKGROUND: Knowledge-based planning (KBP) tools rely on large datasets of clinical plans, which are often difficult to collect, particularly in new o...

Apr 10 2026 41965202
Integrated machine learning and experimental validation reveal S6K2 as a key target of 6PPD-quinone in bladder cancer.

Tire and Road Wear Particles (TRWP) are pervasive environmental contaminants, yet the molecular mechanisms linking their toxic derivative, 6PPD-quinon...

Apr 10 2026 41966021
Artificial Intelligence Across the PSMA Theranostic Continuum in Prostate Cancer.

Prostate cancer is among the most common male malignancies worldwide, with recent advances in molecular imaging and targeted radiopharmaceutical thera...

Apr 10 2026 41966892
Exploring the mechanisms of diethyl phthalate-induced diabetic nephropathy through integrated network toxicology, machine learning, and experimental validation.

Phthalate plasticizers, especially diethyl phthalate (DEP), are linked to metabolic disorders, while their precise role and mechanism in diabetic neph...

Apr 10 2026 41967261
Deep learning on genome-wide association studies to predict the patient-specific risk of radiation-induced erectile dysfunction.

OBJECTIVE: Radiation-induced erectile dysfunction (RIED) is a frequent, unpredictable complication following radiotherapy for prostate cancer. We hypo...

Apr 10 2026 41967608
Scoparone alleviates cisplatin-induced acute kidney injury by inhibiting 5-lipoxygenase-mediated ferroptosis.

Ferroptosis, a regulated form of cell death, plays a critical role in renal tubular epithelial cells during acute kidney injury (AKI). Scoparone, a bi...

Apr 10 2026 41967610
Regulatory B cells and SIVA1-LAG3 immune suppression predict poor prognosis in prostate cancer.

Prostate cancer (PCa) is among the most prevalent malignancies affecting men globally. The immunosuppressive characteristics of the tumor microenviron...

Apr 10 2026 41960835
Association of widespread pain and peak alpha frequency cannot be isolated to a single network.

INTRODUCTION: Peak alpha frequency (PAF), an electroencephalography measure, has gained interest due to its association to pain-related neural process...

Apr 9 2026 41972210
Brain ventricle morphology markers in predicting shunt surgery outcome in idiopathic normal-pressure hydrocephalus.

BACKGROUND: Idiopathic normal pressure hydrocephalus (iNPH) is characterized by a clinical triad of symptoms: abnormal gait, memory problems, and urin...

Apr 9 2026 41957814
OncoEducate: A Pilot Study of Generative AI to Enhance Patient-Clinician Communication in Genitourinary Cancer Care.

OncoEducate is a clinician-supervised generative artificial intelligence (AI) application designed to deliver standardized, regimen-level, plain-langu...

Apr 9 2026 41967073
Cost-effectiveness of an artificial intelligence predictive model for guiding androgen deprivation therapy in intermediate-risk prostate cancer.

The ArteraAI Prostate Test (ArteraAI Inc.) is the first predictive biomarker for benefit of adding short-term androgen deprivation therapy (ADT) to ra...

Apr 9 2026 41967115
An informed monotone neural network for multi-stage chronic kidney disease prediction with integrated GFR estimation.

Chronic kidney disease (CKD) is a progressive condition affecting over 850 million people worldwide, where timely detection and accurate staging are c...

Apr 9 2026 41957220
The relationship between mental health disorders and LUTS.

This narrative review explores the complex relationship between lower urinary tract symptoms (LUTS) and mental health disorders, focusing on the influ...

Apr 8 2026 41996723
Healthcare-associated infections in Italian long-term care facilities: a machine learning analysis of a 12-month cohort.

OBJECTIVES: To estimate the incidence of healthcare-associated infections (HAIs) in Italian long-term care facilities (LTCFs) and to evaluate whether ...

Apr 8 2026 41949171
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