Urology

Multi-omics and machine learning framework reveals ABCG2 as a therapeutic target of Eleven Flavored Shenqi Tablets in clear cell renal cell carcinoma.

ETHNOPHARMACOLOGICAL RELEVANCE: Eleven Flavored Shenqi Tablets (EFST) is a classical multi-herbal pr...

Fully automated volumetric assessment of tumor burden using artificial intelligence on 68Ga-PSMA-11 PET predicts survival after 177Lu-PSMA therapy in metastatic Castration-resistant prostate cancer.

PURPOSE: Despite the rapid development of artificial intelligence (AI)-powered automated segmentatio...

Perioperative Acute Kidney Injury: What's New in 2025?

Perioperative acute kidney injury (AKI) is a frequent complication that affects outcomes well beyond...

Virtual screening and experimental validation of small-molecule compounds targeting AR in prostate cancer.

Prostate cancer ranks as the second most prevalent malignancy among men, with its progression predom...

Prostate cancer and benign prostatic hyperplasia lesions segmentation using diffusion kurtosis imaging, T2*, and R2* mapping with U-Net++ algorithm.

This study aimed to propose a deep learning-based segmentation framework to delineate prostate lesio...

Evaluating the Clinical Competence of Large Language Models in Prostate Cancer Management: A Comparative Study of DeepSeek-R1 and ChatGPT.

BACKGROUND: Large language models (LLMs) have gained prominence in medical applications, yet their p...

Blood urea nitrogen-to-lipid ratios are novel indices inversely associated with anxiety: Insights from NHANES.

BACKGROUND: Anxiety is a highly prevalent mental disorder linked to metabolic and renal dysregulatio...

Associations of Skeletal Muscle Mass and Body Mass Index With Clinical Outcomes in Autosomal-Dominant Polycystic Kidney Disease: An Observational Study.

RATIONALE & OBJECTIVE: Low muscle mass is a risk factor for chronic kidney disease. In this study, w...

Accelerating 2D Kidney Magnetic Resonance Fingerprinting Using Deep Learning Based Tissue Quantification.

BACKGROUND: Magnetic Resonance Fingerprinting (MRF) is a technique that can provide rapid quantifica...

A hybrid decision support system using rule-based and AI methods: the OnCATs knowledge-based framework.

BACKGROUND AND SIGNIFICANCE: Clinical decision support systems (CDSS) can improve evidence-based onc...

Discrimination of urine infrared spectral biomarkers for early-stage chronic kidney disease patients using attenuated total reflectance fourier transform infrared spectrometry.

Chronic Kidney Disease (CKD) is a highly prevalent non-communicable disorder lacking a gold standard...

Development and validation of a nomogram combining PI-RADS v2.1 and clinical indicators for the diagnosis of prostate cancer in patients with PSA ≤ 20 ng/mL.

PURPOSE: This investigation focused on developing a predictive clinical tool that combines biparamet...

Radiomics-based IVIM-DWI for early noninvasive assessment of renal allograft dysfunction.

OBJECTIVE: To develop and rigorously validate radiomics-based predictive models using postoperative ...

Explainable machine learning models for early prediction of acute kidney injury after cardiac surgery.

BACKGROUND: This study aimed to develop a data-driven prediction model for cardiac surgery-associate...

Artificial Intelligence 3D Augmented Reality-guided Robotic Prostatectomy Versus Cognitive MRI Intervention: Results of the Prospective Randomized RIDERS Trial.

BACKGROUND AND OBJECTIVE: Three-dimensional (3D) augmented reality (AR) and artificial intelligence ...

Do patients with renal calculi exhibit viscerosomatic reflexes as evident on CT imaging?

CONTEXT: Experimental evidence supporting the existence of the viscerosomatic reflex highlights an i...

Histopathology-only Artificial Intelligence for Prostate Cancer: Towards Accessible Risk Stratification.

Machine learning prediction of multidrug-resistant urinary tract infections in brain and spinal cord injury patients: a dual-center validation study.

BACKGROUND AND OBJECTIVE: Multidrug-resistant urinary tract infections (MDR UTIs) are a growing conc...

Genomic and Transcriptomic Profiling of High-risk Bladder Cancer Reveals Diverse Molecular and Microenvironment Ecosystems.

BACKGROUND AND OBJECTIVE: High-risk bladder cancer recurs in 30% of cases and causes fatal outcomes ...

Precision Nutritional Genomics, Gut Microbiota and Artificial Intelligence in Chronic Kidney Disease.

Chronic kidney disease (CKD) is a prevalent global health issue, and nutritional management of CKD i...

Illuminating Mouse Renal Proximal Tubule Architecture through High-Resolution Volume EM and Machine Learning Analysis.

KEY POINTS: High-resolution 3D imaging reveals new features of proximal tubule ultrastructure that s...