Urology

Recent advancements in personalized management of prostate cancer biochemical recurrence after radical prostatectomy.

PURPOSE OF REVIEW: Biochemical recurrence (BCR) after radical prostatectomy exhibits heterogeneous p...

Deciphering the Immunomodulatory Function of GSN Inflammatory Cancer-Associated Fibroblasts in Renal Cell Carcinoma Immunotherapy: Insights From Pan-Cancer Single-Cell Landscape and Spatial Transcriptomics Analysis.

The heterogeneity of cancer-associated fibroblasts (CAFs) could affect the response to immune checkp...

An All-in-one Nanohole Array for Size-Exclusive Trapping and High-Throughput Digital Counting of Single Extracellular Vesicles for Non-invasive Cancer Screening.

The analysis of single small extracellular vesicles (sEVs) could distinguish the heterogeneity of sE...

Effects of Hepatic or Renal Impairment on Pharmacokinetics of Fruquintinib.

Fruquintinib (FRUZAQLA) is a highly selective tyrosine kinase inhibitor of all three vascular endoth...

Hypoferremic Response to Chronic Inflammation Is Controlled via the Hemojuvelin/Hepcidin/Ferroportin Axis and Does Not Involve Hepcidin-Independent Regulation of Fpn mRNA.

The iron regulatory hormone hepcidin contributes to the pathogenesis of anemia of inflammation (AI) ...

Push Forward Clinical Management of Hematological Toxicity due to Lenalidomide Overexposure: Model-Informed Precision Dosing for Chinese Population With Renal Insufficiency.

Dose-dependent hematological toxicity of lenalidomide has been reported previously, and thus, there ...

Prostate cancer clinicopathological presentation in South-East Africa during the 2010 decade.

Prostate cancer (PCa) is the leading cause of cancer-associated death amongst men across Sub-Saharan...

Optimizing Fragmentation while Minimizing Thermal Injury Risk with the Thulium Fiber Laser in Ureteral Stone Lithotripsy: An In Vitro Study.

To optimize thulium fiber laser (TFL) settings for effective stone fragmentation although minimizin...

Dual nanozyme sensor enables rapid at-home cancer surveillance.

Early detection of cancer is critical for improving patient survival rates, and current in vitro dia...

Corrigendum to 'Application of AI-MR in the Planning of PCNL for Special Types of Complex Upper Urinary Stones: A Pilot Study' [Urology 196 (2025) 40-47].

PSMA MRI Guided Prostate SABR ARGOS-CLIMBER Phase I/II Trial: A Primary Endpoint Analysis.

PURPOSE: The XXXXX trial is a multi-institutional phase I/II study utilizing a combined PSMA PET/MRI...

Inadequate imipenem dosing in patients with decreased kidney function: A clinical pharmacokinetic study.

OBJECTIVES: A number of population pharmacokinetic (popPK) models of imipenem in critically ill pati...

Analysis of gray zone PSA and PSAD correlated with PIRADS v2.1 in the MRI-US fusion prostate biopsy era: a retrospective bi-centre study.

BACKGROUND: Multiple parameters including PSA, PSAD, and PIRADS v2.1 score, are being associated in ...

Deep learning assisted identification of SCUBE2 and SLC16 A5 combination in RNA-sequencing data as a novel specific potential diagnostic biomarker in prostate cancer.

Despite the extensive use of biomarkers like PSA, AMACR, and PCA3, prostate cancer (PCa) is still a ...

Comparison of Machine Learning Algorithms and Bayesian Estimation in Predicting Tacrolimus Concentration in Tunisian Kidney Transplant Patients During the Early Post-Transplant Period.

BACKGROUND AND OBJECTIVE: Model-informed precision dosing (MIPD), based on a Bayesian approach and m...

AI-driven glomerular morphology quantification: a novel pipeline for assessing basement membrane thickness and podocyte foot process effacement in kidney diseases.

BACKGROUND AND OBJECTIVE: Measuring the thickness of the glomerular basement membrane (GBM) and asse...

Systemic inflammation mediates the relationship between urinary cadmium and chronic cough risk: findings based on multiple statistical models.

Epidemiological research examining the relationship between urinary cadmium and the risk of chronic ...

Mechanisms involved in pro-inflammatory responses to traffic-derived particulate matter (PM) in THP-1 macrophages compared to HBEC3-KT bronchial epithelial cells.

The pro-inflammatory responses in THP-1-derived macrophages and human bronchial epithelial cells (HB...

The added value of artificial intelligence using Quantib Prostate for the detection of prostate cancer at multiparametric magnetic resonance imaging.

PURPOSE: Artificial intelligence (AI) has been proposed to assist radiologists in reporting multipar...

Enhancing Organ Allocation Efficiency: A Pilot Study Evaluating Artificial Intelligence-Assisted Assessment of Donor Kidney Pathology.

PURPOSE: The purpose of this study is to evaluate the effectiveness of an artificial intelligence (A...

Machine learning-derived multivariate renal function trajectories in acute kidney injury in critically ill patients: a multicentre retrospective study.

BACKGROUND: Acute kidney injury (AKI) exhibits considerable heterogeneity. The objective of the curr...