AI Medical Compendium Journal:
Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Showing 111 to 120 of 198 articles

Predicting Single Neuron Responses of the Primary Visual Cortex with Deep Learning Model.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Modeling neuron responses to stimuli can shed light on next-generation technologies such as brain-chip interfaces. Furthermore, high-performing models can serve to help formulate hypotheses and reveal the mechanisms underlying neural responses. Here ...

A Novel Approach Utilizing Domain Adversarial Neural Networks for the Detection and Classification of Selective Sweeps.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
The identification and classification of selective sweeps are of great significance for improving the understanding of biological evolution and exploring opportunities for precision medicine and genetic improvement. Here, a domain adaptation sweep de...

CIRI-Deep Enables Single-Cell and Spatial Transcriptomic Analysis of Circular RNAs with Deep Learning.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Circular RNAs (circRNAs) are a crucial yet relatively unexplored class of transcripts known for their tissue- and cell-type-specific expression patterns. Despite the advances in single-cell and spatial transcriptomics, these technologies face difficu...

De Novo Generation and Identification of Novel Compounds with Drug Efficacy Based on Machine Learning.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
One of the main challenges in small molecule drug discovery is finding novel chemical compounds with desirable activity. Traditional drug development typically begins with target selection, but the correlation between targets and disease remains to b...

BioinspiredLLM: Conversational Large Language Model for the Mechanics of Biological and Bio-Inspired Materials.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
The study of biological materials and bio-inspired materials science is well established; however, surprisingly little knowledge is systematically translated to engineering solutions. To accelerate discovery and guide insights, an open-source autoreg...

Mapping Cell Atlases at the Single-Cell Level.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Recent advancements in single-cell technologies have led to rapid developments in the construction of cell atlases. These atlases have the potential to provide detailed information about every cell type in different organisms, enabling the characteri...

Interactive Multi-Stage Robotic Positioner for Intra-Operative MRI-Guided Stereotactic Neurosurgery.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Magnetic resonance imaging (MRI) demonstrates clear advantages over other imaging modalities in neurosurgery with its ability to delineate critical neurovascular structures and cancerous tissue in high-resolution 3D anatomical roadmaps. However, its ...

Human Motor System-Based Biohybrid Robot-On-a-Chip for Drug Evaluation of Neurodegenerative Disease.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Biohybrid robots have been developed for biomedical applications and industrial robotics. However, the biohybrid robots have limitations to be applied in neurodegenerative disease research due to the absence of a central nervous system. In addition, ...

Deep Learning Empowers the Discovery of Self-Assembling Peptides with Over 10 Trillion Sequences.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Self-assembling of peptides is essential for a variety of biological and medical applications. However, it is challenging to investigate the self-assembling properties of peptides within the complete sequence space due to the enormous sequence quanti...

Structural Electronic Skin for Conformal Tactile Sensing.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
The conformal integration of the electronic skin on the non-developable surface is in great demand for the comprehensive tactile sensing of robotics and prosthetics. However, the current techniques still encounter obstacles in achieving conformal int...