Database : the journal of biological databases and curation
May 15, 2021
Crop phenotypic data underpin many pre-breeding efforts to characterize variation within germplasm collections. Although there has been an increase in the global capacity for accumulating and comparing such data, a lack of consistency in the systemat...
Database : the journal of biological databases and curation
Apr 29, 2021
High-quality metadata annotations for data hosted in large public repositories are essential for research reproducibility and for conducting fast, powerful and scalable meta-analyses. Currently, a majority of sequencing samples in the National Center...
Database : the journal of biological databases and curation
Feb 16, 2021
Omics technologies offer great promises for improving our understanding of diseases. The integration and interpretation of such data pose major challenges, calling for adequate knowledge models. Disease maps provide curated knowledge about disorders'...
Database : the journal of biological databases and curation
Jan 1, 2020
Small open reading frames (ORFs) have been systematically disregarded by automatic genome annotation. The difficulty in finding patterns in tiny sequences is the main reason that makes small ORFs to be overlooked by computational procedures. However,...
Database : the journal of biological databases and curation
Jan 1, 2020
The ability to compare entities within a knowledge graph is a cornerstone technique for several applications, ranging from the integration of heterogeneous data to machine learning. It is of particular importance in the biomedical domain, where seman...
Database : the journal of biological databases and curation
Jan 1, 2020
Congenital heart disease (CHD) is one of the most common birth defects, with complex genetic and environmental etiologies. The reports of genetic variation associated with CHD have increased dramatically in recent years due to the revolutionary devel...
Database : the journal of biological databases and curation
Jan 1, 2020
Due to the concerted efforts to utilize the microbial features to improve disease prediction capabilities, automated machine learning (AutoML) systems aiming to get rid of the tediousness in manually performing ML tasks are in great demand. Here we d...
Database : the journal of biological databases and curation
Jan 1, 2020
Nutrition research can be conducted by using two complementary approaches: (i) traditional self-reporting methods or (ii) via metabolomics techniques to analyze food intake biomarkers in biofluids. However, the complexity and heterogeneity of these t...
Database : the journal of biological databases and curation
Jan 1, 2020
Clinical case reports are the 'eyewitness reports' of medicine and provide a valuable, unique, albeit noisy and underutilized type of evidence. Generally, a case report has a single main finding that represents the reason for writing up the report in...
Database : the journal of biological databases and curation
Jan 1, 2020
In the UniProt Knowledgebase (UniProtKB), publications providing evidence for a specific protein annotation entry are organized across different categories, such as function, interaction and expression, based on the type of data they contain. To prov...