AI Medical Compendium Journal:
Sheng wu gong cheng xue bao = Chinese journal of biotechnology

Showing 21 to 29 of 29 articles

[Construction of Escherichia coli cell factories].

Sheng wu gong cheng xue bao = Chinese journal of biotechnology
As an important model industrial microorganism, Escherichia coli has been widely used in pharmaceutical, chemical industry and agriculture. In the past 30 years, a variety of new strategies and techniques, including artificial intelligence, gene edit...

[Preface for special issue on industrial microorganisms: innovation and breakthrough (2021)].

Sheng wu gong cheng xue bao = Chinese journal of biotechnology
Industrial microorganisms and their products are widely used in various fields such as industry, agriculture, and medicine, which play a pivotal role in economy. Efficient industrial strains are the key to improve production efficiency, and advanced ...

[Research progress of feature selection and machine learning methods for mass spectrometry-based protein biomarker discovery].

Sheng wu gong cheng xue bao = Chinese journal of biotechnology
With the development of mass spectrometry technologies and bioinformatics analysis algorithms, disease research-driven human proteome project (HPP) is advancing rapidly. Protein biomarkers play critical roles in clinical applications and the biomarke...

[Prediction of protein subcellular localization based on multilayer sparse coding].

Sheng wu gong cheng xue bao = Chinese journal of biotechnology
In order to provide a theoretical basis for better understanding the function and properties of proteins, we proposed a simple and effective feature extraction method for protein sequences to determine the subcellular localization of proteins. First,...

[Construction and high-density fermentation of alkaline pectate lyase high-yield yeast].

Sheng wu gong cheng xue bao = Chinese journal of biotechnology
Pectate lyase is widely applied in ramie degumming and fabric bioscouring in the textile industry. Compared to conventional processes that involve high alkaline and high temperature treatment, enzyme based treatments have significant advantages in fi...

[Development, identification and application of 33 monoclonal antibodies against cardiac troponin T].

Sheng wu gong cheng xue bao = Chinese journal of biotechnology
The aim of this study is to prepare and characterize cardiac troponin T (cTnT) monoclonal antibodies (mAb), and further develop a chemiluminescence quantitative detection assay for cTnT. BALB/c mice were immunized with recombinant cTnT antigen, and s...

[Gene optimization and efficient expression of Trichoderma reesei Cel5A in Pichia pastoris].

Sheng wu gong cheng xue bao = Chinese journal of biotechnology
Deficient activity of endo-1,4-beta-glucanase II (Cel5A) secreted by Trichoderma reesei is one of the challenges involved in effective cellulase saccharification of cellulosic substrates. Therefore, we expressed Cel5A in Pichia pastoris by constructi...

[Enhancement of Coprinus cinereus peroxidase in Pichia pastoris by co-expression chaperone PDI and Ero1].

Sheng wu gong cheng xue bao = Chinese journal of biotechnology
The 1,095 bp gene encoding peroxidase from Coprinus cinereus was synthesized and integrated into the genome of Pichia pastoris with a highly inducible alcohol oxidase. The recombinant CiP (rCiP) fused with the a-mating factor per-pro leader sequence ...

[Collagen quantitation by detection of marker peptides with HPLC-MS].

Sheng wu gong cheng xue bao = Chinese journal of biotechnology
A method for quantitation of collagen was established by detecting marker peptide with high performance liquid chromatography-mass spectrometry (HPLC-MS). Theoretical marker peptides were selected by sequence comparison. Bovine collagen type I was di...