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Action Potentials

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A machine-learning approach for long-term prediction of experimental cardiac action potential time series using an autoencoder and echo state networks.

Chaos (Woodbury, N.Y.)
Computational modeling and experimental/clinical prediction of the complex signals during cardiac arrhythmias have the potential to lead to new approaches for prevention and treatment. Machine-learning (ML) and deep-learning approaches can be used fo...

Coherent oscillations in balanced neural networks driven by endogenous fluctuations.

Chaos (Woodbury, N.Y.)
We present a detailed analysis of the dynamical regimes observed in a balanced network of identical quadratic integrate-and-fire neurons with sparse connectivity for homogeneous and heterogeneous in-degree distributions. Depending on the parameter va...

Surrogate gradients for analog neuromorphic computing.

Proceedings of the National Academy of Sciences of the United States of America
To rapidly process temporal information at a low metabolic cost, biological neurons integrate inputs as an analog sum, but communicate with spikes, binary events in time. Analog neuromorphic hardware uses the same principles to emulate spiking neural...

THE ROLE OF BURSTS IN SENSORY DISCRIMINATION AND RETENTION OF FAVORED INPUTS IN THE CULTURED NEURAL NETWORKS.

Georgian medical news
The capacity of neural tissue to discriminiate the sensory signals determines how we recognise the world diversity. Dissociated cortical culture (DCC) homed in a multielectrode array allows mimicking neural networks of the brain and using it for inve...

Dynamic Spatiotemporal Pattern Recognition With Recurrent Spiking Neural Network.

Neural computation
Our real-time actions in everyday life reflect a range of spatiotemporal dynamic brain activity patterns, the consequence of neuronal computation with spikes in the brain. Most existing models with spiking neurons aim at solving static pattern recogn...

Deep learning approaches for neural decoding across architectures and recording modalities.

Briefings in bioinformatics
Decoding behavior, perception or cognitive state directly from neural signals is critical for brain-computer interface research and an important tool for systems neuroscience. In the last decade, deep learning has become the state-of-the-art method i...

Transition to synchronization in heterogeneous inhibitory neural networks with structured synapses.

Chaos (Woodbury, N.Y.)
Inhibitory neurons form an extensive network involved in the development of different rhythms in the cerebral cortex. A transition from an incoherent state, where all inhibitory neurons fire unrelated to each other, to a synchronized or locked state,...

Inverse mechano-electrical reconstruction of cardiac excitation wave patterns from mechanical deformation using deep learning.

Chaos (Woodbury, N.Y.)
The inverse mechano-electrical problem in cardiac electrophysiology is the attempt to reconstruct electrical excitation or action potential wave patterns from the heart's mechanical deformation that occurs in response to electrical excitation. Becaus...

Validation of a Convolutional Neural Network Model for Spike Transformation Using a Generalized Linear Model.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Identification of causal relationships of neural activity is one of the most important problems in neuroscience and neural engineering. We show that a novel deep learning approach using a convolutional neural network to model output neural spike acti...