IEEE/ACM transactions on computational biology and bioinformatics
Dec 8, 2021
Non-coding RNA (ncRNA) is involved in many biological processes and diseases in all species. Many ncRNA datasets exist that provide ncRNA data in FASTA format which is well suited for biomedical purposes. However, for ncRNA analysis and classificatio...
IEEE/ACM transactions on computational biology and bioinformatics
Dec 8, 2021
Myocardial infarctions and heart failure are the cause of more than 17 million deaths annually worldwide. ST-segment elevation myocardial infarctions (STEMI) require timely treatment, because delays of minutes have serious clinical impacts. Machine l...
IEEE/ACM transactions on computational biology and bioinformatics
Dec 8, 2021
The identification of a protein fold type from its amino acid sequence provides important insights about the protein 3D structure. In this paper, we propose a deep learning architecture that can process protein residue-level features to address the p...
IEEE/ACM transactions on computational biology and bioinformatics
Dec 8, 2021
Protein fold recognition is critical for studies of the protein structure prediction and drug design. Several methods have been proposed to obtain discriminative features from the protein sequences for fold recognition. However, the ensemble methods ...
IEEE/ACM transactions on computational biology and bioinformatics
Dec 8, 2021
Identifying interactions between drugs and target proteins is a critical step in the drug development process, as it helps identify new targets for drugs and accelerate drug development. The number of known drug-protein interactions (positive samples...
IEEE/ACM transactions on computational biology and bioinformatics
Dec 8, 2021
Understanding the ageing process is a very challenging problem for biologists. To help in this task, there has been a growing use of classification methods (from machine learning) to learn models that predict whether a gene influences the process of ...
IEEE/ACM transactions on computational biology and bioinformatics
Dec 8, 2021
Over the years, numerous evidences have demonstrated that microbes living in the human body are closely related to human life activities and human diseases. However, traditional biological experiments are time-consuming and expensive, so it has becom...
IEEE/ACM transactions on computational biology and bioinformatics
Dec 8, 2021
Molecular biomarkers are certain molecules or set of molecules that can be of help for diagnosis or prognosis of diseases or disorders. In the past decades, thanks to the advances in high-throughput technologies, a huge amount of molecular 'omics' da...
IEEE/ACM transactions on computational biology and bioinformatics
Dec 8, 2021
The global alignment of biological networks (GABN) aims to find an optimal alignment between proteins across species, such that both the biological structures and the topological structures of the proteins are maximally conserved. The research on GAB...
IEEE/ACM transactions on computational biology and bioinformatics
Dec 8, 2021
The recent advances in wet-lab automation enable high-throughput experiments to be conducted seamlessly. In particular, the exhaustive enumeration of all possible conditions is always involved in high-throughput screening. Nonetheless, such a screeni...
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