AIMC Topic: Algorithms

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Predicting Adverse Drug-Drug Interactions with Neural Embedding of Semantic Predications.

AMIA ... Annual Symposium proceedings. AMIA Symposium
The identification of drug-drug interactions (DDIs) is important for patient safety; yet, compared to other pharmacovigilance work, a limited amount of research has been conducted in this space. Recent work has successfully applied a method of derivi...

Identifying Cancer Patients at Risk for Heart Failure Using Machine Learning Methods.

AMIA ... Annual Symposium proceedings. AMIA Symposium
Cardiotoxicity related to cancer therapies has become a serious issue, diminishing cancer treatment outcomes and quality of life. Early detection of cancer patients at risk for cardiotoxicity before cardiotoxic treatments and providing preventive mea...

Using Natural Language Processing to improve EHR Structured Data-based Surgical Site Infection Surveillance.

AMIA ... Annual Symposium proceedings. AMIA Symposium
Surgical Site Infection surveillance in healthcare systems is labor intensive and plagued by underreporting as current methodology relies heavily on manual chart review. The rapid adoption of electronic health records (EHRs) has the potential to allo...

Deep learning computer vision algorithm for detecting kidney stone composition.

BJU international
OBJECTIVES: To assess the recall of a deep learning (DL) method to automatically detect kidney stones composition from digital photographs of stones.

Identification of elders at higher risk for fall with statewide electronic health records and a machine learning algorithm.

International journal of medical informatics
OBJECTIVE: Predicting the risk of falls in advance can benefit the quality of care and potentially reduce mortality and morbidity in the older population. The aim of this study was to construct and validate an electronic health record-based fall risk...

Tapping on the Black Box: How Is the Scoring Power of a Machine-Learning Scoring Function Dependent on the Training Set?

Journal of chemical information and modeling
In recent years, protein-ligand interaction scoring functions derived through machine-learning are repeatedly reported to outperform conventional scoring functions. However, several published studies have questioned that the superior performance of m...

AppendiXNet: Deep Learning for Diagnosis of Appendicitis from A Small Dataset of CT Exams Using Video Pretraining.

Scientific reports
The development of deep learning algorithms for complex tasks in digital medicine has relied on the availability of large labeled training datasets, usually containing hundreds of thousands of examples. The purpose of this study was to develop a 3D d...

Graph embedding and unsupervised learning predict genomic sub-compartments from HiC chromatin interaction data.

Nature communications
Chromatin interaction studies can reveal how the genome is organized into spatially confined sub-compartments in the nucleus. However, accurately identifying sub-compartments from chromatin interaction data remains a challenge in computational biolog...

Image segmentation based on gray level and local relative entropy two dimensional histogram.

PloS one
Though traditional thresholding methods are simple and efficient, they may result in poor segmentation results because only image's brightness information is taken into account in the procedure of threshold selection. Considering the contextual infor...

Review and comparative analysis of machine learning-based phage virion protein identification methods.

Biochimica et biophysica acta. Proteins and proteomics
Phage virion protein (PVP) identification plays key role in elucidating relationships between phages and hosts. Moreover, PVP identification can facilitate the design of related biochemical entities. Recently, several machine learning approaches have...