Computational intelligence and neuroscience
Feb 1, 2015
Spiking neurons are models designed to simulate, in a realistic manner, the behavior of biological neurons. Recently, it has been proven that this type of neurons can be applied to solve pattern recognition problems with great efficiency. However, th...
IEEE transactions on neural networks and learning systems
Jan 30, 2015
We present a framework for the identification of spatiotemporal linear dynamical systems. We use a state-space model representation that has the following attributes: 1) the number of spatial observation locations are decoupled from the model order; ...
IEEE transactions on neural networks and learning systems
Jan 30, 2015
This paper develops a neural network architecture and a new processing method for solving in real time, the nonlinear equality constrained multiobjective optimization problem (NECMOP), where several nonlinear objective functions must be optimized in ...
We present a novel interactive segmentation framework incorporating a priori knowledge learned from training data. The knowledge is learned as a structured patch model (StPM) comprising sets of corresponding local patch priors and their pairwise spat...
Since Ambros' discovery of small non-protein coding RNAs in the early 1990s, the past two decades have seen an upsurge in the number of reports of predicted microRNAs (miR), which have been implicated in various functions. The correlation of miRs wit...
Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research
Jan 29, 2015
Traditional analytic methods are often ill-suited to the evolving world of health care big data characterized by massive volume, complexity, and velocity. In particular, methods are needed that can estimate models efficiently using very large dataset...
The epilepsies are a heterogeneous group of neurological disorders and syndromes characterised by recurrent, involuntary, paroxysmal seizure activity, which is often associated with a clinicoelectrical correlate on the electroencephalogram. The diagn...
Journal of neuroimaging : official journal of the American Society of Neuroimaging
Jan 28, 2015
BACKGROUND: Alzheimer's disease (AD) patients show early changes in white matter (WM) structural integrity. We studied the use of diffusion tensor imaging (DTI) in assessing WM alterations in the predementia stage of mild cognitive impairment (MCI).
The study of biomolecular interactions between a drug and its biological target is of paramount importance for the design of novel bioactive compounds. In this paper, we report on the use of molecular dynamics (MD) simulations and machine learning to...
Prognostics is a core process of prognostics and health management (PHM) discipline, that estimates the remaining useful life (RUL) of a degrading machinery to optimize its service delivery potential. However, machinery operates in a dynamic environm...
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