Alzheimer's Disease (AD) is an irreversible, degenerative condition that, while incurable, can have its progression slowed or impeded. While there are numerous methods utilizing neural networks for AD detection, there is a scarcity of High-performanc...
BACKGROUND: There is a broad interest in deploying deep learning-based classification algorithms to identify individuals with Alzheimer's disease (AD) from healthy controls (HC) based on neuroimaging data, such as T1-weighted Magnetic Resonance Imagi...
Accurate and scalable quantification of amyloid-β (Aβ) pathology is crucial for deeper disease phenotyping and furthering research in Alzheimer Disease (AD). This multidisciplinary study addresses the current limitations on neuropathology by leveragi...
BACKGROUND: The early diagnosis of Alzheimer's disease (AD) and mild cognitive impairment (MCI) remains a significant challenge in neurology, with conventional methods often limited by subjectivity and variability in interpretation. Integrating deep...
Alzheimer's & dementia : the journal of the Alzheimer's Association
Aug 14, 2024
INTRODUCTION: The incidence of Alzheimer's disease (AD) and obesity rise concomitantly. This study examined whether factors affecting metabolism, race/ethnicity, and sex are associated with AD development.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry
Aug 10, 2024
OBJECTIVE: The current evidence regarding how different predictor domains contributes to predicting incident dementia remains unclear. This study aims to assess the incremental value of five predictor domains when added to a simple dementia risk pred...
Accurate mapping of brain functional subregions at an individual level is crucial. Task-based functional MRI (tfMRI) captures subject-specific activation patterns during various functions and behaviors, facilitating the individual localization of fun...
IEEE/ACM transactions on computational biology and bioinformatics
Aug 8, 2024
Alzheimer's is progressive and irreversible type of dementia, which causes degeneration and death of cells and their connections in the brain. AD worsens over time and greatly impacts patients' life and affects their important mental functions, inclu...
IEEE/ACM transactions on computational biology and bioinformatics
Aug 8, 2024
Randomized shallow/deep neural networks with closed form solution avoid the shortcomings that exist in the back propagation (BP) based trained neural networks. Ensemble deep random vector functional link (edRVFL) network utilize the strength of two g...
IEEE/ACM transactions on computational biology and bioinformatics
Aug 8, 2024
Multimodal learning is widely used in automated early diagnosis of Alzheimer's disease. However, the current studies are based on an assumption that different modalities can provide more complementary information to help classify the samples from the...