AIMC Topic: Animals

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Deep learning-based high-resolution time inference for deciphering dynamic gene regulation from fixed embryos.

Nature communications
Embryo development is driven by the spatiotemporal dynamics of complex gene regulatory networks. Uncovering these dynamics requires simultaneous tracking of multiple fluctuating molecular species over time, which exceeds the capabilities of tradition...

Surgical embodied intelligence for generalized task autonomy in laparoscopic robot-assisted surgery.

Science robotics
Surgical robots capable of autonomously performing various tasks could enhance efficiency and augment human productivity in addressing clinical needs. Although current solutions have automated specific actions within defined contexts, they are challe...

Artificial intelligence tools to assess different levels of activity performed by semi-wild horses in grassland ecosystems.

Environmental monitoring and assessment
In order to understand the role of horses in ecosystems and to effectively use their grazing in the protection of grasslands, it is important to assess where they primarily stay, followed by whether these habitats are used for grazing or resting. The...

EUP: Enhanced cross-species prediction of ubiquitination sites via a conditional variational autoencoder network based on ESM2.

PLoS computational biology
Ubiquitination is critical in biomedical research. Predicting ubiquitination sites based on deep learning model have advanced the study of ubiquitination. However, traditional supervised model limits in the scenarios where labels are scarcity across ...

The intelligent evaluation model of the English humanistic landscape in agricultural industrial parks by the SPEAKING model: From the perspective of fish-vegetable symbiosis in new agriculture.

PloS one
To more accurately capture the expression of the English humanistic landscape in agricultural industrial parks under the emerging agricultural paradigm of fish-vegetable symbiosis, and to address the limitations of unscientific evaluation standards a...

Molecular mechanisms of efferocytosis imbalance in the idiopathic pulmonary fibrosis microenvironment: from gene screening to dynamic regulation analysis.

Biology direct
BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a chronic progressive pulmonary disease characterized by alveolar structural destruction and fibrosis. In recent years, efferocytosis has been recognized as playing a crucial role in the occurrence a...

DeepEthoProfile-Rapid Behavior Recognition in Long-Term Recorded Home-Cage Mice.

eNeuro
Animal behavior is crucial for understanding both normal brain function and dysfunction. To facilitate behavior analysis of mice within their home environments, we developed DeepEthoProfile, an open-source software powered by a deep convolutional neu...

CalTrig: A GUI-Based Machine Learning Approach for Decoding Neuronal Calcium Transients in Freely Moving Rodents.

eNeuro
Advances in in vivo Ca imaging using miniature microscopes have enabled researchers to study single-neuron activity in freely moving animals. Tools such as Minian and CalmAn have been developed to convert Ca visual signals to numerical data, collecti...

Identification and experimental validation of BMX as a crucial PANoptosis‑related gene for immune response in Spinal Cord Injury.

PloS one
Spinal cord injury (SCI) is a debilitating neurological condition that severely impacts motor, sensory, and autonomic functions, leading to significant challenges in patient quality of life and imposing substantial economic burdens on society. PANopt...

Identification of necroptotic biomarkers associated with immune microenvironment in sepsis based on the protein-protein interaction network and machine learning.

Clinica chimica acta; international journal of clinical chemistry
BACKGROUND: Necroptosis is inflammatorily sparked and closely associated with sepsis, but the crosstalk between necroptosis and inflammation in sepsis has rarely been studied in depth. This study is designed to reveal the role of necroptosis in the p...