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Islets of Langerhans Transplantation

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Safety and feasibility of the robotic platform in the management of surgical sequelae of chronic pancreatitis.

Surgical endoscopy
BACKGROUND/AIM: The application of minimally invasive surgery to chronic pancreatitis (CP) procedures is uncommon. Our objective was to report the safety and feasibility of the robotic approach in the treatment of surgical sequelae of CP, and provide...

Simultaneous spatiotemporal tracking and oxygen sensing of transient implants in vivo using hot-spot MRI and machine learning.

Proceedings of the National Academy of Sciences of the United States of America
A varying oxygen environment is known to affect cellular function in disease as well as activity of various therapeutics. For transient structures, whether they are unconstrained therapeutic transplants, migrating cells during tumor metastasis, or ce...

Artificial Intelligence Analysis of Magnetic Particle Imaging for Islet Transplantation in a Mouse Model.

Molecular imaging and biology
PURPOSE: Current approaches to quantification of magnetic particle imaging (MPI) for cell-based therapy are thwarted by the lack of reliable, standardized methods of segmenting the signal from background in images. This calls for the development of a...

Robot-Assisted Total Pancreatectomy With Autologous Islet Cell Transplantation: Perioperative Nursing Considerations.

AORN journal
Chronic pancreatitis (CP) is an inflammatory disease of the pancreas that causes pain and gastrointestinal problems in patients. Robot-assisted total pancreatectomy with autologous islet cell transplantation (TPAIT) is a surgical procedure for treati...

Generalizability of machine learning models for diabetes detection a study with nordic islet transplant and PIMA datasets.

Scientific reports
Diabetes Mellitus (DM) is a global health challenge, and accurate early detection is critical for effective management. The study explores the potential of machine learning for improved diabetes prediction using microarray gene expression data and PI...