AIMC Topic: Animals

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Raman spectroscopy in tandem with machine learning - based decision logic methods for characterization and detection of primary precancerous and cancerous cells.

The Analyst
Early cancer detection improves patient outcomes, but most Raman spectroscopy research has focused on discriminating between normal and malignant cells, ignoring the essential precancerous stage. This study fills that gap by combining Raman spectrosc...

The Icarian flight of antibody-drug conjugates: target selection amidst complexity and tackling adverse impacts.

Protein & cell
Antibody-drug conjugates (ADCs) represent a promising class of targeted cancer therapeutics that combine the specificity of monoclonal antibodies with the potency of cytotoxic payloads. Despite their therapeutic potential, the use of ADCs faces signi...

Identifying environmental drivers of Aedes aegypti and Aedes albopictus abundance in the Dallas-Fort Worth metroplex using Random Forest modeling.

Journal of medical entomology
Aedes aegypti and Aedes albopictus are 2 medically important vectors that have established populations globally. In the United States, Ae. aegypti populations declined post-Ae. albopictus introduction, though both species now can be readily found thr...

Exploring Neural Dynamics in the Auditory Telencephalon of Crows Using Functional Ultrasound Imaging.

The Journal of neuroscience : the official journal of the Society for Neuroscience
Crows, renowned for advanced cognitive abilities and vocal communication, rely on intricate auditory systems. While the neuroanatomy of corvid auditory pathways is partially explored, the underlying neurophysiological mechanisms are largely unknown. ...

[Advances in mechanotransduction signaling pathways in distraction osteogenesis].

Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery
OBJECTIVE: To review the role and research progress of mechanotransduction signaling pathway in distraction osteogenesis, so as to provide theoretical basis and reference for clinical treatment.

Nutritionally Responsive PMv DAT Neurons Are Dynamically Regulated During Pubertal Transition.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Pubertal development is tightly regulated by energy balance. The crosstalk between metabolism and reproduction is orchestrated by complex neural networks, and leptin action in the hypothalamus plays a critical role. The ventral premammillary nucleus ...

Predictive modeling and interpretability analysis of bioconcentration factors for organic chemicals in fish using machine learning.

Environmental pollution (Barking, Essex : 1987)
Chemicals are misused and released into the environment, causing adverse effects on people and ecosystems. Assessing the potential environmental risks of these chemicals before their use is crucial. The bioconcentration factor (BCF) is a key paramete...

Applying deep learning algorithms for non-invasive estimation of carotenoid content in the foot muscle of Pacific abalone with different colors.

Food chemistry
Carotenoids are vital pigments influencing both the coloration and health of aquatic organisms, particularly in species such as the Pacific abalone (Haliotis discus hannai). In this study, we identified the major carotenoids in abalone foot muscle us...

Mechanically Matched Heart-on-a-Chip Platform Mediated Maturation of Excitation-Contraction Coupling.

ACS nano
Heart-on-a-chip (HOC) platforms play a pivotal role in cardiac research, yet existing models suffer from mechanical mismatch between the soft myocardial tissue, sensors, and substrate, leading to impaired myocardial function and compromised data capt...

Analytical Data Review on an Artificial Intelligence Platform for Doping Control in Horse Racing.

Analytical chemistry
In the screening of prohibited substances (PS) in horse biological samples with gas chromatography/mass spectrometry (GC/MS) and liquid chromatography/mass spectrometry (LC/MS) for doping control, an enormous number of chromatograms are generated. Re...