AIMC Topic: Bone Regeneration

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Divide-and-conquer strategy with engineered ossification center organoids for rapid bone healing through developmental cell recruitment.

Nature communications
Current approaches for bone repair predominantly target localized delivery of growth factors that are aimed at the coupling of angiogenesis and osteogenesis. However, delayed revascularization and regeneration of critical-sized bone defects are still...

Discovering novel type I collagen fragments from Cyprinus carpio supporting bone regeneration.

Functional & integrative genomics
Fish collagen is gaining increasing attention in tissue engineering due to its exceptional bioactivity. This study aimed to isolate functional fish collagen fragments capable of microbial biosynthesis and supporting bone tissue regeneration. Collagen...

Optimal structural characteristics of osteoinductivity in bioceramics derived from a novel high-throughput screening plus machine learning approach.

Biomaterials
Osteoinduction is an important feature of the next generation of bone repair materials. But the key structural factors and parameters of osteoinductive scaffolds are not yet clarified. This study leverages the efficiency of high-throughput screening ...

Assessment of hard tissue changes after horizontal guided bone regeneration with the aid of deep learning CBCT segmentation.

Clinical oral investigations
OBJECTIVES: To investigate the performance of a deep learning (DL) model for segmenting cone-beam computed tomography (CBCT) scans taken before and after mandibular horizontal guided bone regeneration (GBR) to evaluate hard tissue changes.

Modeling new trends in bone regeneration, using the BERTopic approach.

Regenerative medicine
Bibliometric surveys are time-consuming endeavors, which cannot be scaled up to meet the challenges of ever-expanding fields, such as bone regeneration. Artificial intelligence, however, can provide smart tools to screen massive amounts of literatur...

The future of bone regeneration: integrating AI into tissue engineering.

Biomedical physics & engineering express
Tissue engineering is a branch of regenerative medicine that harnesses biomaterial and stem cell research to utilise the body's natural healing responses to regenerate tissue and organs. There remain many unanswered questions in tissue engineering, w...

[Advances in mechanotransduction signaling pathways in distraction osteogenesis].

Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery
OBJECTIVE: To review the role and research progress of mechanotransduction signaling pathway in distraction osteogenesis, so as to provide theoretical basis and reference for clinical treatment.

Generative Artificial Intelligence in Dental Implants.

Studies in health technology and informatics
Generative Artificial Intelligence holds promising applications in dentistry, revolutionizing various aspects of patient care, treatment planning, and education. One key application is the creation of realistic 3D models of dental structures, enablin...

AI-Enabled Exoskeletal Robotics for Enhancing Mobility, Bone Regeneration, and Functional Rehabilitation in Osteoporosis: A Literature Review.

Studies in health technology and informatics
The care of osteoporosis is being revolutionized by developments in AI-enabled exoskeletal robotics, which can improve mobility and facilitate the recovery from fragility fractures. The literature on current advancements in exoskeletal robotics and t...

[rhPDGF-BB promotes migration of bone marrow stromal stem cells in diabetic rats].

Shanghai kou qiang yi xue = Shanghai journal of stomatology
PURPOSE: To evaluate the effect of different concentrations of rhPDGF-BB on bone marrow stromal stem cells(BMSCs) migration in diabetic rat, and related mechanisms of SDF-1 and its G-protein conjugated receptor regulation, provide a theoretical basis...