AIMC Topic: Angiotensin Receptor Antagonists

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Natural language processing of electronic medical records identifies cardioprotective agents for anthracycline induced cardiotoxicity.

Scientific reports Feb 24, 2025
In this retrospective observational study, we aimed to investigate the potential of natural language processing (NLP) for drug repositioning by analyzing the preventive effects of cardioprotective drugs against anthracycline-induced cardiotoxicity (A...
Drug Repositioning Natural Language Processing Calcium Channel Blockers Adult Male Middle Aged Cardiotonic Agents Cardiotoxicity Anthracyclines Adrenergic beta-Antagonists Hydroxymethylglutaryl-CoA Reductase Inhibitors Angiotensin Receptor Antagonists Angiotensin-Converting Enzyme Inhibitors Humans Female Aged Retrospective Studies Electronic Health Records
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A retrospective prognostic evaluation using unsupervised learning in the treatment of COVID-19 patients with hypertension treated with ACEI/ARB drugs.

PeerJ May 13, 2024
INTRODUCTION: This study aimed to evaluate the prognosis of patients with COVID-19 and hypertension who were treated with angiotensin-converting enzyme inhibitor (ACEI)/angiotensin receptor B (ARB) drugs and to identify key features affecting patient...
Humans Retrospective Studies Female SARS-CoV-2 Aged COVID-19 Algorithms Prognosis Angiotensin Receptor Antagonists Angiotensin-Converting Enzyme Inhibitors Cluster Analysis Unsupervised Machine Learning Male COVID-19 Drug Treatment Middle Aged Hypertension
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The Role of GDF-15 in Heart Failure Patients With Chronic Kidney Disease.

The Canadian journal of cardiology Dec 26, 2018
BACKGROUND: Growth differentiation factor-15 (GDF-15) is a stress-inducible cytokine and member of the transforming growth factor-β cytokine superfamily that refines prognostic assessment in subgroups of patients with heart failure (HF). We evaluated...
Angiotensin-Converting Enzyme Inhibitors Growth Differentiation Factor 15 Heart Failure, Systolic Heart-Assist Devices Natriuretic Peptide, Brain Glomerular Filtration Rate Angiotensin Receptor Antagonists Follow-Up Studies Male Cholesterol Humans Heart Transplantation Blood Pressure Middle Aged Sodium Biomarkers Proportional Hazards Models Renal Insufficiency, Chronic Sex Factors Female Systole
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Machine Learning Methods Improve Prognostication, Identify Clinically Distinct Phenotypes, and Detect Heterogeneity in Response to Therapy in a Large Cohort of Heart Failure Patients.

Journal of the American Heart Association Apr 12, 2018
BACKGROUND: Whereas heart failure (HF) is a complex clinical syndrome, conventional approaches to its management have treated it as a singular disease, leading to inadequate patient care and inefficient clinical trials. We hypothesized that applying ...
Cardiovascular Agents Adrenergic beta-Antagonists Diuretics Angiotensin Receptor Antagonists Angiotensin-Converting Enzyme Inhibitors Humans Machine Learning Ventricular Function, Left Algorithms Stroke Volume Retrospective Studies Middle Aged Aged, 80 and over Female Follow-Up Studies Reproducibility of Results Survival Rate Phenotype Registries Sweden Prognosis Male Heart Failure Aged
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Sacubitril/Valsartan in an Elderly Patient with Heart Failure: A Case Report.

Cardiology Dec 21, 2017
Sacubitril/valsartan has recently been approved for the treatment of heart failure with reduced ejection fraction. Given its recent introduction in the armamentarium for the treatment of heart failure (HF), "field-practice" evidence is required to de...
Aged, 80 and over Male Stroke Volume Echocardiography Valsartan Humans Drug Combinations Angiotensin Receptor Antagonists Heart Failure Heart Ventricles Tetrazoles Aminobutyrates Biphenyl Compounds
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Innovative spectrophotometric methods for simultaneous estimation of the novel two-drug combination: Sacubitril/Valsartan through two manipulation approaches and a comparative statistical study.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy Dec 17, 2017
Different innovative spectrophotometric methods were introduced for the first time for simultaneous quantification of sacubitril/valsartan in their binary mixture and in their combined dosage form without prior separation through two manipulation app...
Statistics as Topic Spectrophotometry Valsartan Angiotensin Receptor Antagonists Tetrazoles Aminobutyrates Drug Combinations Biphenyl Compounds Tablets
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