AIMC Topic: Biological Ontologies

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Toward a standard formal semantic representation of the model card report.

BMC bioinformatics
BACKGROUND: Model card reports aim to provide informative and transparent description of machine learning models to stakeholders. This report document is of interest to the National Institutes of Health's Bridge2AI initiative to address the FAIR chal...

Anatomy and the type concept in biology show that ontologies must be adapted to the diagnostic needs of research.

Journal of biomedical semantics
BACKGROUND: In times of exponential data growth in the life sciences, machine-supported approaches are becoming increasingly important and with them the need for FAIR (Findable, Accessible, Interoperable, Reusable) and eScience-compliant data and met...

A vector-based semantic relatedness measure using multiple relations within SNOMED CT and UMLS.

Journal of biomedical informatics
OBJECTIVE: To propose a new vector-based relatedness metric that derives word vectors from the intrinsic structure of biomedical ontologies, without consulting external resources such as large-scale biomedical corpora.

An automated process for supporting decisions in clustering-based data analysis.

Computer methods and programs in biomedicine
BACKGROUND AND OBJECTIVE: Metrics are commonly used by biomedical researchers and practitioners to measure and evaluate properties of individuals, instruments, models, methods, or datasets. Due to the lack of a standardized validation procedure for a...

The Xenopus phenotype ontology: bridging model organism phenotype data to human health and development.

BMC bioinformatics
BACKGROUND: Ontologies of precisely defined, controlled vocabularies are essential to curate the results of biological experiments such that the data are machine searchable, can be computationally analyzed, and are interoperable across the biomedical...

Design and Evaluation of a Postpartum Depression Ontology.

Applied clinical informatics
OBJECTIVE: Postpartum depression (PPD) remains an understudied research area despite its high prevalence. The goal of this study is to develop an ontology to aid in the identification of patients with PPD and to enable future analyses with electronic...

A multipurpose TNM stage ontology for cancer registries.

Journal of biomedical semantics
BACKGROUND: Population-based cancer registries are a critical reference source for the surveillance and control of cancer. Cancer registries work extensively with the internationally recognised TNM classification system used to stage solid tumours, b...

Semantic Search for Large Scale Clinical Ontologies.

AMIA ... Annual Symposium proceedings. AMIA Symposium
Finding concepts in large clinical ontologies can be challenging when queries use different vocabularies. A search algorithm that overcomes this problem is useful in applications such as concept normalisation and ontology matching, where concepts can...

The BMS-LM ontology for biomedical data reporting throughout the lifecycle of a research study: From data model to ontology.

Journal of biomedical informatics
Biomedical research data reuse and sharing is essential for fostering research progress. To this aim, data producers need to master data management and reporting through standard and rich metadata, as encouraged by open data initiatives such as the F...

Ontology-based identification and prioritization of candidate drugs for epilepsy from literature.

Journal of biomedical semantics
BACKGROUND: Drug repurposing can improve the return of investment as it finds new uses for existing drugs. Literature-based analyses exploit factual knowledge on drugs and diseases, e.g. from databases, and combine it with information from scholarly ...