Journal of bioinformatics and computational biology
Oct 1, 2018
Multifunctional genes are important genes because of their essential roles in human cells. Studying and analyzing multifunctional genes can help understand disease mechanisms and drug discovery. We propose a computational method for scoring gene mult...
With the development of the omic technologies, the acquisition approaches of various biological data on different levels and types are becoming more mature. As a large amount of data will be produced in the process of diagnosis and treatment of disea...
MOTIVATION: Creating large datasets for biomedical relation classification can be prohibitively expensive. While some datasets have been curated to extract protein-protein and drug-drug interactions (PPIs and DDIs) from text, we are also interested i...
Journal of the American Medical Informatics Association : JAMIA
Jul 1, 2018
OBJECTIVE: To automatically recognize self-acknowledged limitations in clinical research publications to support efforts in improving research transparency.
A major ambition of artificial intelligence lies in translating patient data to successful therapies. Machine learning models face particular challenges in biomedicine, however, including handling of extreme data heterogeneity and lack of mechanistic...
Ninety per cent of the world's data have been generated in the last 5 years ( Report no. DES4702. Issued April 2017. Royal Society). A small fraction of these data is collected with the aim of validating specific hypotheses. These studies are led by ...
MOTIVATION: In biomedical research, chemical is an important class of entities, and chemical named entity recognition (NER) is an important task in the field of biomedical information extraction. However, most popular chemical NER methods are based o...