AIMC Topic: Carbapenem-Resistant Enterobacteriaceae

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Machine Learning and DIA Proteomics Reveal New Insights into Carbapenem Resistance Mechanisms in .

Journal of proteome research Jul 7, 2025
The emergence of Carbapenem-resistant (CRKP) represents a major public health concern, primarily driven by its ability to evade a wide range of antibiotics. Despite extensive genomic studies, proteomic insights into antibiotic resistance mechanisms ...
Anti-Bacterial Agents Drug Resistance, Bacterial Klebsiella pneumoniae Humans Machine Learning beta-Lactamases Carbapenems Carbapenem-Resistant Enterobacteriaceae Proteomics Klebsiella Infections Bacterial Proteins
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Rapid detection of carbapenem-resistant Escherichia coli and carbapenem-resistant Klebsiella pneumoniae in positive blood cultures via MALDI-TOF MS and tree-based machine learning models.

BMC microbiology Jan 24, 2025
BACKGROUND: Bloodstream infection (BSI) is a systemic infection that predisposes individuals to sepsis and multiple organ dysfunction syndrome. Early identification of infectious agents and determination of drug-resistant phenotypes can help patients...
Klebsiella pneumoniae Bacteremia Blood Culture Anti-Bacterial Agents Microbial Sensitivity Tests Escherichia coli Infections Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization Carbapenems Klebsiella Infections Escherichia coli Decision Trees Humans Machine Learning Carbapenem-Resistant Enterobacteriaceae
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A novel approach to antimicrobial resistance: Machine learning predictions for carbapenem-resistant Klebsiella in intensive care units.

International journal of medical informatics Dec 7, 2024
This study was conducted at Kocaeli University Hospital in Turkey and aimed to predict carbapenem-resistant Klebsiella pneumoniae infection in intensive care units using the Extreme Gradient Boosting (XGBoost) algorithm, a form of artificial intellig...
Turkey Carbapenems Drug Resistance, Bacterial Carbapenem-Resistant Enterobacteriaceae Retrospective Studies Case-Control Studies Intensive Care Units Klebsiella pneumoniae Machine Learning Female Male Klebsiella Infections Aged Algorithms Middle Aged Adult Anti-Bacterial Agents Humans
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Modelling the rapid detection of Carbapenemase-resistant Klebsiella pneumoniae based on machine learning and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.

Diagnostic microbiology and infectious disease Jul 30, 2024
In this study, 80 carbapenem-resistant Klebsiella pneumoniae (CR-KP) and 160 carbapenem-susceptible Klebsiella pneumoniae (CS-KP) strains detected in the clinic were selected and their matrix-assisted laser desorption/ionization time-of-flight mass s...
Klebsiella pneumoniae Klebsiella Infections Bacterial Proteins beta-Lactamases Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization Sensitivity and Specificity Microbial Sensitivity Tests ROC Curve Machine Learning Humans Anti-Bacterial Agents Carbapenem-Resistant Enterobacteriaceae
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Raman spectrum combined with deep learning for precise recognition of Carbapenem-resistant Enterobacteriaceae.

Analytical and bioanalytical chemistry Feb 21, 2024
Carbapenem-resistant Enterobacteriaceae (CRE) is a major pathogen that poses a serious threat to human health. Unfortunately, currently, there are no effective measures to curb its rapid development. To address this, an in-depth study on the surface-...
Humans Silver Carbapenem-Resistant Enterobacteriaceae Anti-Bacterial Agents Deep Learning Spectrum Analysis, Raman
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Detection of carbapenem-resistant Klebsiella pneumoniae on the basis of matrix-assisted laser desorption ionization time-of-flight mass spectrometry by using supervised machine learning approach.

PloS one Feb 6, 2020
BACKGROUND: Carbapenem-resistant Klebsiella pneumoniae (CRKP) is emerging as a significant pathogen causing healthcare-associated infections. Matrix-assisted laser desorption/ionisation mass spectrometry time-of-flight mass spectrometry (MALDI-TOF MS...
Carbapenem-Resistant Enterobacteriaceae Random Amplified Polymorphic DNA Technique Carbapenems Cross Infection DNA, Bacterial Anti-Bacterial Agents Humans Klebsiella Infections Algorithms Predictive Value of Tests Microbial Sensitivity Tests Supervised Machine Learning Klebsiella pneumoniae Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
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Rapid Identification and Typing of Carbapenem-Resistant Klebsiella pneumoniae Using MALDI-TOF MS and Machine Learning.

Microbial biotechnology Jun 1, 2025
Use matrix-assisted laser desorption ionisation time-of-flight mass spectrometry (MALDI-TOF MS) to screen the specific mass peaks of carbapenem-resistant Klebsiella pneumoniae (CRKP), compare the differences in spectrum peaks between intestinal and b...
Klebsiella Infections Machine Learning Bacterial Proteins Humans Carbapenems Sensitivity and Specificity Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization Klebsiella pneumoniae Bacterial Typing Techniques Carbapenem-Resistant Enterobacteriaceae
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