AIMC Topic: Carbapenem-Resistant Enterobacteriaceae

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Rapid detection of carbapenem-resistant Escherichia coli and carbapenem-resistant Klebsiella pneumoniae in positive blood cultures via MALDI-TOF MS and tree-based machine learning models.

BMC microbiology Jan 24, 2025
BACKGROUND: Bloodstream infection (BSI) is a systemic infection that predisposes individuals to sepsis and multiple organ dysfunction syndrome. Early identification of infectious agents and determination of drug-resistant phenotypes can help patients...
Anti-Bacterial Agents Microbial Sensitivity Tests Klebsiella pneumoniae Humans Machine Learning Decision Trees Escherichia coli Infections Carbapenems Carbapenem-Resistant Enterobacteriaceae Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization Klebsiella Infections Escherichia coli Bacteremia Blood Culture
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A novel approach to antimicrobial resistance: Machine learning predictions for carbapenem-resistant Klebsiella in intensive care units.

International journal of medical informatics Dec 7, 2024
This study was conducted at Kocaeli University Hospital in Turkey and aimed to predict carbapenem-resistant Klebsiella pneumoniae infection in intensive care units using the Extreme Gradient Boosting (XGBoost) algorithm, a form of artificial intellig...
Carbapenems Carbapenem-Resistant Enterobacteriaceae Klebsiella Infections Turkey Adult Male Case-Control Studies Klebsiella pneumoniae Middle Aged Humans Machine Learning Anti-Bacterial Agents Drug Resistance, Bacterial Algorithms Retrospective Studies Intensive Care Units Female Aged
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Modelling the rapid detection of Carbapenemase-resistant Klebsiella pneumoniae based on machine learning and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.

Diagnostic microbiology and infectious disease Jul 30, 2024
In this study, 80 carbapenem-resistant Klebsiella pneumoniae (CR-KP) and 160 carbapenem-susceptible Klebsiella pneumoniae (CS-KP) strains detected in the clinic were selected and their matrix-assisted laser desorption/ionization time-of-flight mass s...
Anti-Bacterial Agents Humans Sensitivity and Specificity beta-Lactamases Machine Learning ROC Curve Microbial Sensitivity Tests Klebsiella Infections Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization Klebsiella pneumoniae Bacterial Proteins Carbapenem-Resistant Enterobacteriaceae
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Raman spectrum combined with deep learning for precise recognition of Carbapenem-resistant Enterobacteriaceae.

Analytical and bioanalytical chemistry Feb 21, 2024
Carbapenem-resistant Enterobacteriaceae (CRE) is a major pathogen that poses a serious threat to human health. Unfortunately, currently, there are no effective measures to curb its rapid development. To address this, an in-depth study on the surface-...
Anti-Bacterial Agents Silver Deep Learning Carbapenem-Resistant Enterobacteriaceae Spectrum Analysis, Raman Humans
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Detection of carbapenem-resistant Klebsiella pneumoniae on the basis of matrix-assisted laser desorption ionization time-of-flight mass spectrometry by using supervised machine learning approach.

PloS one Feb 6, 2020
BACKGROUND: Carbapenem-resistant Klebsiella pneumoniae (CRKP) is emerging as a significant pathogen causing healthcare-associated infections. Matrix-assisted laser desorption/ionisation mass spectrometry time-of-flight mass spectrometry (MALDI-TOF MS...
Klebsiella pneumoniae Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization Cross Infection Random Amplified Polymorphic DNA Technique DNA, Bacterial Carbapenem-Resistant Enterobacteriaceae Anti-Bacterial Agents Carbapenems Klebsiella Infections Predictive Value of Tests Humans Microbial Sensitivity Tests Supervised Machine Learning Algorithms
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Rapid Identification and Typing of Carbapenem-Resistant Klebsiella pneumoniae Using MALDI-TOF MS and Machine Learning.

Microbial biotechnology Jun 1, 2025
Use matrix-assisted laser desorption ionisation time-of-flight mass spectrometry (MALDI-TOF MS) to screen the specific mass peaks of carbapenem-resistant Klebsiella pneumoniae (CRKP), compare the differences in spectrum peaks between intestinal and b...
Sensitivity and Specificity Humans Klebsiella pneumoniae Carbapenems Bacterial Typing Techniques Bacterial Proteins Klebsiella Infections Carbapenem-Resistant Enterobacteriaceae Machine Learning Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
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