AIMC Topic: Carnosine

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Building the drug-GO function network to screen significant candidate drugs for myasthenia gravis.

PloS one Apr 4, 2019
Myasthenia gravis (MG) is an autoimmune disease. In recent years, considerable evidence has indicated that Gene Ontology (GO) functions, especially GO-biological processes, have important effects on the mechanisms and treatments of different diseases...
Humans Gene Regulatory Networks Genetic Association Studies Databases, Genetic Immunosuppressive Agents Drug Repositioning Thalidomide Zinc Compounds Adalimumab Glucosamine Carnosine Organometallic Compounds Gene Ontology Myasthenia Gravis Databases, Pharmaceutical Pharmacogenomic Testing Etanercept
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l-Carnosine supplementation attenuated fasting glucose, triglycerides, advanced glycation end products, and tumor necrosis factor-α levels in patients with type 2 diabetes: a double-blind placebo-controlled randomized clinical trial.

Nutrition research (New York, N.Y.) Nov 17, 2017
Considering the pathologic importance of metabolic disturbances, advanced glycation end products (AGEs), and chronic inflammation in diabetes mellitus and ameliorating potentials of l-carnosine in hampering these detritions and because these effects ...
Humans Tumor Necrosis Factor-alpha Female Adult Male Middle Aged Fasting Blood Glucose Diabetes Mellitus, Type 2 Dietary Supplements Adipose Tissue Double-Blind Method Body Composition Glycated Hemoglobin Arginine Triglycerides Lysine Glycation End Products, Advanced Carnosine
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