AIMC Topic: Thalidomide

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Prevalence of fungal colonization among patients with psoriasis in difficult-to-treat areas: impact of apremilast on mycotic burden and clinical outcomes.

Frontiers in immunology Dec 10, 2024
INTRODUCTION: Fungi, including , may be a trigger or exacerbate psoriasis, especially in difficult to treat (DTT) areas, through the activation of IL-17/23 axis.
Aged Adult Cytokines Anti-Inflammatory Agents, Non-Steroidal Thalidomide Prevalence Female Male Psoriasis Humans Middle Aged Treatment Outcome Candida Candidiasis
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The effect of thalidomide on the invasive ability of gastric cancer cells by regulating miR-524-5p/FSTL1.

Cellular and molecular biology (Noisy-le-Grand, France) Dec 20, 2023
This study aimed to investigate the effect of thalidomide (Thal) regulating microRNA (miR)-524-5p/follistatin-like protein 1 (FSTL1) on the invasion ability of gastric cancer cells. For this purpose, real-time fluorescent quantitative PCR (RT-qPCR) w...
MicroRNAs Thalidomide Matrix Metalloproteinase 9 Humans Follistatin-Related Proteins Cell Proliferation Cell Movement Stomach Neoplasms Cell Line, Tumor Matrix Metalloproteinase 2 Luciferases
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Building the drug-GO function network to screen significant candidate drugs for myasthenia gravis.

PloS one Apr 4, 2019
Myasthenia gravis (MG) is an autoimmune disease. In recent years, considerable evidence has indicated that Gene Ontology (GO) functions, especially GO-biological processes, have important effects on the mechanisms and treatments of different diseases...
Humans Organometallic Compounds Gene Ontology Glucosamine Carnosine Pharmacogenomic Testing Etanercept Myasthenia Gravis Databases, Pharmaceutical Databases, Genetic Drug Repositioning Immunosuppressive Agents Thalidomide Gene Regulatory Networks Zinc Compounds Genetic Association Studies Adalimumab
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Pharmacokinetics and Safety of Elotuzumab Combined With Lenalidomide and Dexamethasone in Patients With Multiple Myeloma and Various Levels of Renal Impairment: Results of a Phase Ib Study.

Clinical lymphoma, myeloma & leukemia Dec 21, 2015
INTRODUCTION: The present study evaluated the pharmacokinetics and safety of elotuzumab, a humanized IgG1 monoclonal antibody against signaling lymphocyte activation molecule-F7, combined with lenalidomide and dexamethasone, in patients with multiple...
Dexamethasone Multiple Myeloma Thalidomide Neoplasm Staging Retreatment Lenalidomide Cytogenetic Analysis Treatment Outcome Kidney Function Tests Antibodies, Monoclonal, Humanized Kidney Diseases Severity of Illness Index Antineoplastic Combined Chemotherapy Protocols Middle Aged Aged Aged, 80 and over Adult Humans Male Female
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