AIMC Topic: CD4 Lymphocyte Count
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Predicting the immunological nonresponse to antiretroviral therapy in people living with HIV: a machine learning-based multicenter large-scale study.
Frontiers in cellular and infection microbiology
Mar 11, 2025
BACKGROUND: Although highly active antiretroviral therapy (HAART) has greatly enhanced the prognosis for people living with HIV (PLWH), some individuals fail to achieve adequate immune reconstitution, known as immunological nonresponse (INR), which i...
HIV-positive patients with oral Kaposi's sarcoma: An overall survival analysis of 31 patients.
Oral surgery, oral medicine, oral pathology and oral radiology
Nov 20, 2020
OBJECTIVE: The aim of this study was to evaluate the influence of viral load and lymphocyte count on survival of patients who presented with human immunodeficiency virus (HIV)-associated oral Kaposi's sarcoma.
Random forest machine learning algorithm predicts virologic outcomes among HIV infected adults in Lausanne, Switzerland using electronically monitored combined antiretroviral treatment adherence.
AIDS care
Apr 8, 2020
Machine Learning (ML) can improve the analysis of complex and interrelated factors that place adherent people at risk of viral rebound. Our aim was to build ML model to predict RNA viral rebound from medication adherence and clinical data. Patients w...
Alendronate/Vitamin D for attenuating bone mineral density loss during antiretroviral initiation: a pilot randomized controlled trial.
HIV research & clinical practice
Feb 27, 2020
Antiretroviral therapy (ART) initiation is associated with decreases in bone mineral density (BMD). To plan for a larger trial, we sought to obtain preliminary estimates for the difference in the change in BMD at 48 weeks achieved with 24 weeks of p...
A comparative study of logistic regression based machine learning techniques for prediction of early virological suppression in antiretroviral initiating HIV patients.
BMC medical informatics and decision making
Sep 4, 2018
BACKGROUND: Treatment with effective antiretroviral therapy (ART) lowers morbidity and mortality among HIV positive individuals. Effective highly active antiretroviral therapy (HAART) should lead to undetectable viral load within 6 months of initiati...
HHV-8-associated haemophagocytic lymphohistiocytosis in a patient with advanced AIDS.
BMJ case reports
Dec 22, 2017
We present a patient with advanced AIDS admitted with recurrent shock of unclear aetiology, fevers, altered mental status and refractory cytopenias. His case posed a diagnostic challenge because evaluation of septic shock in the setting of advanced A...
Tuberculous Pericarditis is Multibacillary and Bacterial Burden Drives High Mortality.
EBioMedicine
Sep 21, 2015
BACKGROUND: Tuberculous pericarditis is considered to be a paucibacillary process; the large pericardial fluid accumulation is attributed to an inflammatory response to tuberculoproteins. Mortality rates are high. We investigated the role of clinical...
High frequency of neurosyphilis in HIV-positive patients diagnosed with early syphilis.
HIV medicine
Sep 10, 2015
BACKGROUND: Syphilis is an infection frequently seen with HIV, and European guidelines on the management of syphilis suggest that HIV-infected patients may have an increased risk of early neurological involvement, sometimes asymptomatic. Recent study...
Efficacy and Tolerability of Tenofovir/Lamivudine/Dolutegravir among Antiretroviral Therapy Naive Human Immunodeficiency Virus Infected Patients of a Tertiary Care Center in Eastern India.
The Journal of the Association of Physicians of India
Sep 1, 2023
BACKGROUND: Although many drug regimens have been used in the treatment of human immunodeficiency virus (HIV) infection, the National AIDS Control Organization (NACO) of India recommends the use of a fixed-dose combination of tenofovir/lamivudine/dol...
[Virological evolution of patients with HIV infection that start antiretroviral therapy with a very high baseline viral load].
Revista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia
Dec 1, 2021
BACKGROUND: The degree of viral suppression in HIV patients who start antiretroviral therapy (ART) with very high viral loads (CV) is unknown.
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