AIMC Topic: Lymphohistiocytosis, Hemophagocytic

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Predicting 30-day mortality in hemophagocytic lymphohistiocytosis: clinical features, biochemical parameters, and machine learning insights.

Annals of hematology Mar 1, 2025
This study aims to evaluate the clinical characteristics and biochemical parameters of hemophagocytic lymphohistiocytosis (HLH) patients to predict 30-day mortality. Parameters analyzed include lymphocyte count (L), platelet count (PLT), total protei...
Humans Child, Preschool Child Middle Aged Adolescent Platelet Count Lymphohistiocytosis, Hemophagocytic ROC Curve Nomograms Female Young Adult Adult Male Prognosis Machine Learning Retrospective Studies
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Machine Learning of Laboratory Data in Predicting 30-Day Mortality for Adult Hemophagocytic Lymphohistiocytosis.

Journal of clinical immunology Sep 20, 2024
BACKGROUND: Hemophagocytic Lymphohistiocytosis (HLH) carries a high mortality rate. Current existing risk-evaluation methodologies fall short and improved predictive methods are needed. This study aimed to forecast 30-day mortality in adult HLH patie...
Adult Male Aged Young Adult Lymphohistiocytosis, Hemophagocytic Middle Aged ROC Curve Algorithms Prognosis Retrospective Studies Female Humans Machine Learning
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Etiological stratification and prognostic assessment of haemophagocytic lymphohistiocytosis by machine learning on onco-mNGS data and clinical data.

Frontiers in immunology Sep 9, 2024
INTRODUCTION: Hemophagocytic lymphohistiocytosis (HLH) is a rare, complicated and life threatening hyperinflammatory syndrome that maybe triggered by various infectious agents, malignancies and rheumatologic disorders. Early diagnosis and identificat...
Lymphohistiocytosis, Hemophagocytic Female Young Adult Adult Child, Preschool Male Child Infant Machine Learning Humans Epstein-Barr Virus Infections Middle Aged Adolescent Prognosis DNA Copy Number Variations Neoplasms
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HHV-8-associated haemophagocytic lymphohistiocytosis in a patient with advanced AIDS.

BMJ case reports Dec 22, 2017
We present a patient with advanced AIDS admitted with recurrent shock of unclear aetiology, fevers, altered mental status and refractory cytopenias. His case posed a diagnostic challenge because evaluation of septic shock in the setting of advanced A...
Fever Dexamethasone Shock, Septic Anti-Inflammatory Agents Herpesvirus 8, Human Male Bone Marrow Acquired Immunodeficiency Syndrome Lymphohistiocytosis, Hemophagocytic Humans Fatal Outcome Middle Aged Diagnosis, Differential Herpesviridae Infections CD4 Lymphocyte Count
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