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Cell Nucleus

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Fluorescent Neuronal Cells v2: multi-task, multi-format annotations for deep learning in microscopy.

Scientific data
Fluorescent Neuronal Cells v2 is a collection of fluorescence microscopy images and the corresponding ground-truth annotations, designed to foster innovative research in the domains of Life Sciences and Deep Learning. This dataset encompasses three i...

CellViT: Vision Transformers for precise cell segmentation and classification.

Medical image analysis
Nuclei detection and segmentation in hematoxylin and eosin-stained (H&E) tissue images are important clinical tasks and crucial for a wide range of applications. However, it is a challenging task due to nuclei variances in staining and size, overlapp...

NuInsSeg: A fully annotated dataset for nuclei instance segmentation in H&E-stained histological images.

Scientific data
In computational pathology, automatic nuclei instance segmentation plays an essential role in whole slide image analysis. While many computerized approaches have been proposed for this task, supervised deep learning (DL) methods have shown superior s...

Comprehensive data analysis of white blood cells with classification and segmentation by using deep learning approaches.

Cytometry. Part A : the journal of the International Society for Analytical Cytology
Deep learning approaches have frequently been used in the classification and segmentation of human peripheral blood cells. The common feature of previous studies was that they used more than one dataset, but used them separately. No study has been fo...

Impact of imperfect annotations on CNN training and performance for instance segmentation and classification in digital pathology.

Computers in biology and medicine
Segmentation and classification of large numbers of instances, such as cell nuclei, are crucial tasks in digital pathology for accurate diagnosis. However, the availability of high-quality datasets for deep learning methods is often limited due to th...

Cyto R-CNN and CytoNuke Dataset: Towards reliable whole-cell segmentation in bright-field histological images.

Computer methods and programs in biomedicine
BACKGROUND AND OBJECTIVE: Cell segmentation in bright-field histological slides is a crucial topic in medical image analysis. Having access to accurate segmentation allows researchers to examine the relationship between cellular morphology and clinic...

Utilizing convolutional neural networks for discriminating cancer and stromal cells in three-dimensional cell culture images with nuclei counterstain.

Journal of biomedical optics
SIGNIFICANCE: Accurate cell segmentation and classification in three-dimensional (3D) images are vital for studying live cell behavior and drug responses in 3D tissue culture. Evaluating diverse cell populations in 3D cell culture over time necessita...

A deep learning-based toolkit for 3D nuclei segmentation and quantitative analysis in cellular and tissue context.

Development (Cambridge, England)
We present a new set of computational tools that enable accurate and widely applicable 3D segmentation of nuclei in various 3D digital organs. We have developed an approach for ground truth generation and iterative training of 3D nuclear segmentation...

aiSEGcell: User-friendly deep learning-based segmentation of nuclei in transmitted light images.

PLoS computational biology
Segmentation is required to quantify cellular structures in microscopic images. This typically requires their fluorescent labeling. Convolutional neural networks (CNNs) can detect these structures also in only transmitted light images. This eliminate...

Structure Embedded Nucleus Classification for Histopathology Images.

IEEE transactions on medical imaging
Nuclei classification provides valuable information for histopathology image analysis. However, the large variations in the appearance of different nuclei types cause difficulties in identifying nuclei. Most neural network based methods are affected ...