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Histocytochemistry

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A method for utilizing automated machine learning for histopathological classification of testis based on Johnsen scores.

Scientific reports
We examined whether a tool for determining Johnsen scores automatically using artificial intelligence (AI) could be used in place of traditional Johnsen scoring to support pathologists' evaluations. Average precision, precision, and recall were asses...

Adaptive adversarial neural networks for the analysis of lossy and domain-shifted datasets of medical images.

Nature biomedical engineering
In machine learning for image-based medical diagnostics, supervised convolutional neural networks are typically trained with large and expertly annotated datasets obtained using high-resolution imaging systems. Moreover, the network's performance can...

Learning from crowds in digital pathology using scalable variational Gaussian processes.

Scientific reports
The volume of labeled data is often the primary determinant of success in developing machine learning algorithms. This has increased interest in methods for leveraging crowds to scale data labeling efforts, and methods to learn from noisy crowd-sourc...

Classification of subtypes including LCNEC in lung cancer biopsy slides using convolutional neural network from scratch.

Scientific reports
Identifying the lung carcinoma subtype in small biopsy specimens is an important part of determining a suitable treatment plan but is often challenging without the help of special and/or immunohistochemical stains. Pathology image analysis that tackl...

The Evolving Role of Artificial Intelligence in Gastrointestinal Histopathology: An Update.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
Significant advances in artificial intelligence (AI) over the past decade potentially may lead to dramatic effects on clinical practice. Digitized histology represents an area ripe for AI implementation. We describe several current needs within the w...

Sliding Window Optimal Transport for Open World Artifact Detection in Histopathology.

IEEE journal of biomedical and health informatics
Histological images are frequently impaired by local artifacts from scanner malfunctions or iatrogenic processes - caused by preparation - impacting the performance of Deep Learning models. Models often struggle with the slightest out-of-distribution...

An Automated Framework for Histopathological Nucleus Segmentation With Deep Attention Integrated Networks.

IEEE/ACM transactions on computational biology and bioinformatics
Clinical management and accurate disease diagnosis are evolving from qualitative stage to the quantitative stage, particularly at the cellular level. However, the manual process of histopathological analysis is lab-intensive and time-consuming. Meanw...

DCNNLFS: A Dilated Convolutional Neural Network With Late Fusion Strategy for Intelligent Classification of Gastric Histopathology Images.

IEEE journal of biomedical and health informatics
Gastric cancer has a high incidence rate, significantly threatening patients' health. Gastric histopathology images can reliably diagnose related diseases. Still, the data volume of histopathology images is too large, making misdiagnosis or missed di...

Structure Embedded Nucleus Classification for Histopathology Images.

IEEE transactions on medical imaging
Nuclei classification provides valuable information for histopathology image analysis. However, the large variations in the appearance of different nuclei types cause difficulties in identifying nuclei. Most neural network based methods are affected ...

Self-Supervised Representation Distribution Learning for Reliable Data Augmentation in Histopathology WSI Classification.

IEEE transactions on medical imaging
Multiple instance learning (MIL) based whole slide image (WSI) classification is often carried out on the representations of patches extracted from WSI with a pre-trained patch encoder. The performance of classification relies on both patch-level rep...