AIMC Topic: Cerebral Cortex

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EEG-based image classification via a region-level stacked bi-directional deep learning framework.

BMC medical informatics and decision making
BACKGROUND: As a physiological signal, EEG data cannot be subjectively changed or hidden. Compared with other physiological signals, EEG signals are directly related to human cortical activities with excellent temporal resolution. After the rapid dev...

Structured sequence processing and combinatorial binding: neurobiologically and computationally informed hypotheses.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences
Understanding how the brain forms representations of structured information distributed in time is a challenging endeavour for the neuroscientific community, requiring computationally and neurobiologically informed approaches. The neural mechanisms f...

Disentangling brain functional network remodeling in corticobasal syndrome - A multimodal MRI study.

NeuroImage. Clinical
OBJECTIVE: The clinical diagnosis of corticobasal syndrome (CBS) represents a challenge for physicians and reliable diagnostic imaging biomarkers would support the diagnostic work-up. We aimed to investigate the neural signatures of CBS using multimo...

Integrating functional connectivity and MVPA through a multiple constraint network analysis.

NeuroImage
Traditional general linear model-based brain mapping efforts using functional neuroimaging are complemented by more recent multivariate pattern analyses (MVPA) that apply machine learning techniques to identify the cognitive states associated with re...

Big Data Challenges Targeting Proteins in GPCR Signaling Pathways; Combining PTML-ChEMBL Models and [S]GTPγS Binding Assays.

ACS chemical neuroscience
G-protein-coupled receptors (GPCRs), also known as 7-transmembrane receptors, are the single largest class of drug targets. Consequently, a large amount of preclinical assays having GPCRs as molecular targets has been released to public sources like ...

Convergent evolution of face spaces across human face-selective neuronal groups and deep convolutional networks.

Nature communications
The discovery that deep convolutional neural networks (DCNNs) achieve human performance in realistic tasks offers fresh opportunities for linking neuronal tuning properties to such tasks. Here we show that the face-space geometry, revealed through pa...

Automatic Seizure Detection Based on S-Transform and Deep Convolutional Neural Network.

International journal of neural systems
Automatic seizure detection is significant for the diagnosis of epilepsy and reducing the massive workload of reviewing continuous EEGs. In this work, a novel approach, combining Stockwell transform (S-transform) with deep Convolutional Neural Networ...

Task-Dependent Changes in the Large-Scale Dynamics and Necessity of Cortical Regions.

Neuron
Neural activity throughout the cortex is correlated with perceptual decisions, but inactivation studies suggest that only a small number of areas are necessary for these behaviors. Here we show that the number of required cortical areas and their dyn...

Visual Evoked Response Modulation Occurs in a Complementary Manner Under Dynamic Circuit Framework.

IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society
The steady-state visual-evoked potential (SSVEP) induced by the periodic visual stimulus plays an important role in vision research. An increasing number of studies use the SSVEP to manipulate intrinsic oscillation and further regulate test performan...

Quantifying brain metabolism from FDG-PET images into a probability of Alzheimer's dementia score.

Human brain mapping
F-fluorodeoxyglucose positron emission tomography (FDG-PET) enables in-vivo capture of the topographic metabolism patterns in the brain. These images have shown great promise in revealing the altered metabolism patterns in Alzheimer's disease (AD). ...