AIMC Topic: Cerebral Cortex

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Revealing unobserved factors underlying cortical activity with a rectified latent variable model applied to neural population recordings.

Journal of neurophysiology
The activity of sensory cortical neurons is not only driven by external stimuli but also shaped by other sources of input to the cortex. Unlike external stimuli, these other sources of input are challenging to experimentally control, or even observe,...

Differential diagnosis of mild cognitive impairment and Alzheimer's disease using structural MRI cortical thickness, hippocampal shape, hippocampal texture, and volumetry.

NeuroImage. Clinical
This paper presents a brain T1-weighted structural magnetic resonance imaging (MRI) biomarker that combines several individual MRI biomarkers (cortical thickness measurements, volumetric measurements, hippocampal shape, and hippocampal texture). The ...

Detection of Mild Traumatic Brain Injury by Machine Learning Classification Using Resting State Functional Network Connectivity and Fractional Anisotropy.

Journal of neurotrauma
Traumatic brain injury (TBI) may adversely affect a person's thinking, memory, personality, and behavior. While mild TBI (mTBI) diagnosis is challenging, there is a risk for long-term psychiatric, neurologic, and psychosocial problems in some patient...

Modeling the N400 ERP component as transient semantic over-activation within a neural network model of word comprehension.

Cognition
The study of the N400 event-related brain potential has provided fundamental insights into the nature of real-time comprehension processes, and its amplitude is modulated by a wide variety of stimulus and context factors. It is generally thought to r...

A neural network model for visual selection and shifting.

Journal of integrative neuroscience
In this paper, a two-layer network is built to simulate the mechanism of visual selection and shifting based on the mapping dynamic model for instantaneous frequency. Unlike the differential equation model using limit cycle to simulate neuron oscilla...

Multi-parameter machine learning approach to the neuroanatomical basis of developmental dyslexia.

Human brain mapping
Despite decades of research, the anatomical abnormalities associated with developmental dyslexia are still not fully described. Studies have focused on between-group comparisons in which different neuroanatomical measures were generally explored in i...

A Hybrid Multishape Learning Framework for Longitudinal Prediction of Cortical Surfaces and Fiber Tracts Using Neonatal Data.

Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention
Dramatic changes of the human brain during the first year of postnatal development are poorly understood due to their multifold complexity. In this paper, we present the first attempt to jointly predict, using neonatal data, the dynamic growth patter...

Predicting symptom severity in autism spectrum disorder based on cortical thickness measures in agglomerative data.

NeuroImage
Machine learning approaches have been widely used for the identification of neuropathology from neuroimaging data. However, these approaches require large samples and suffer from the challenges associated with multi-site, multi-protocol data. We prop...

Uncertainty Quantification of Oscillation Suppression During DBS in a Coupled Finite Element and Network Model.

IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society
Models of the cortico-basal ganglia network and volume conductor models of the brain can provide insight into the mechanisms of action of deep brain stimulation (DBS). In this study, the coupling of a network model, under parkinsonian conditions, to ...

Disentangling disorders of consciousness: Insights from diffusion tensor imaging and machine learning.

Human brain mapping
Previous studies have suggested that disorders of consciousness (DOC) after severe brain injury may result from disconnections of the thalamo-cortical system. However, thalamo-cortical connectivity differences between vegetative state (VS), minimally...