AIMC Topic: Computer Simulation

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Testing on continuous production of mefenamic acids-Design of experiment through simulation and process optimisation.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
In the pharmaceutical manufacturing industry, continuous production methods have been recognised as providing several benefits compared to traditional batch production. These benefits include increased flexibility, higher product output, enhanced qua...

A neural network model for the evolution of reconstructive social learning.

Scientific reports
Learning from others is an important adaptation. However, the evolution of social learning and its role in the spread of socially transmitted information are not well understood. Few models of social learning account for the fact that socially transm...

Research on noninvasive electrophysiologic imaging based on cardiac electrophysiology simulation and deep learning methods for the inverse problem.

BMC cardiovascular disorders
BACKGROUND: The risk stratification and prognosis of cardiac arrhythmia depend on the individual condition of patients, while invasive diagnostic methods may be risky to patient health, and current non-invasive diagnostic methods are applicable to fe...

Spectral integrated neural networks with large time steps for 2D and 3D transient elastodynamic analysis.

Neural networks : the official journal of the International Neural Network Society
This paper provides a neural network architecture, called spectral integrated neural networks (SINNs), designed to tackle two- and three-dimensional elastodynamic problems. In the SINNs, the second-order time derivatives of displacements are approxim...

Generalization and differentiation of affective associative memory circuit based on memristive neural network with emotion transfer.

Neural networks : the official journal of the International Neural Network Society
Most existing research on affective associative memory neural network circuits has predominantly concentrated on reinforcement and extinction, with insufficient attention given to the integration of emotion transfer alongside the principles of genera...

An interpretable approach to estimate the self-motion in fish-like robots using mode decomposition analysis.

Nature communications
The artificial lateral line system, composed of velocity and pressure sensors, is the sensing system for fish-like robots by mimicking the lateral line system of aquatic organisms. However, accurately estimating the self-motion of the fish-like robot...

Titania: an integrated tool for in silico molecular property prediction and NAM-based modeling.

Molecular diversity
Advances in drug discovery and material design rely heavily on in silico analysis of extensive compound datasets and accurate assessment of their properties and activities through computational methods. Efficient and reliable prediction of molecular ...

Dynamic simulation of knee joint mechanics: individualized multi-moment finite element modelling of patellar tendon stress during landing.

Journal of biomechanics
Patellar tendinopathy is prevalent in sports requiring high jumping demands, and understanding the in vivo biomechanical behavior of the patellar tendon (PT) during landing is crucial for developing effective injury prevention and rehabilitation stra...

Reversible kink instability drives ultrafast jumping in nematodes and soft robots.

Science robotics
Entomopathogenic nematodes (EPNs) exhibit a bending-elastic instability, or kink, before becoming airborne, a feature previously hypothesized but not substantiated to enhance jumping performance. Here, we provide the evidence that this kink is crucia...

Computational models for prediction of m6A sites using deep learning.

Methods (San Diego, Calif.)
RNA modifications play a crucial role in enhancing the structural and functional diversity of RNA molecules and regulating various stages of the RNA life cycle. Among these modifications, N6-Methyladenosine (m6A) is the most common internal modificat...