AIMC Topic: Computer Simulation

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Attractor dynamics of a Boolean model of a brain circuit controlled by multiple parameters.

Chaos (Woodbury, N.Y.)
Studies of Boolean recurrent neural networks are briefly introduced with an emphasis on the attractor dynamics determined by the sequence of distinct attractors observed in the limit cycles. We apply this framework to a simplified model of the basal ...

Propagation delays determine neuronal activity and synaptic connectivity patterns emerging in plastic neuronal networks.

Chaos (Woodbury, N.Y.)
In plastic neuronal networks, the synaptic strengths are adapted to the neuronal activity. Specifically, spike-timing-dependent plasticity (STDP) is a fundamental mechanism that modifies the synaptic strengths based on the relative timing of pre- and...

Towards an accurate and efficient heuristic for species/gene tree co-estimation.

Bioinformatics (Oxford, England)
MOTIVATION: Species and gene trees represent how species and individual loci within their genomes evolve from their most recent common ancestors. These trees are central to addressing several questions in biology relating to, among other issues, spec...

DeepSol: a deep learning framework for sequence-based protein solubility prediction.

Bioinformatics (Oxford, England)
MOTIVATION: Protein solubility plays a vital role in pharmaceutical research and production yield. For a given protein, the extent of its solubility can represent the quality of its function, and is ultimately defined by its sequence. Thus, it is imp...

Reference Trajectory Adaptation to Improve Human-Robot Interaction: A Database-Driven Approach.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Many robotic devices that are used for therapy or as assistive devices rely on pre-defined reference trajectories to assist the user's movements. Fixed pre-defined trajectories force the user to adapt to unnatural movement patterns which may be detri...

DLBI: deep learning guided Bayesian inference for structure reconstruction of super-resolution fluorescence microscopy.

Bioinformatics (Oxford, England)
MOTIVATION: Super-resolution fluorescence microscopy with a resolution beyond the diffraction limit of light, has become an indispensable tool to directly visualize biological structures in living cells at a nanometer-scale resolution. Despite advanc...

γ-Aminobutyric Acid Type A Receptor Potentiation Inhibits Learning in a Computational Network Model.

Anesthesiology
BACKGROUND: Propofol produces memory impairment at concentrations well below those abolishing consciousness. Episodic memory, mediated by the hippocampus, is most sensitive. Two potentially overlapping scenarios may explain how γ-aminobutyric acid re...

Evaluation of a new neutron energy spectrum unfolding code based on an Adaptive Neuro-Fuzzy Inference System (ANFIS).

Journal of radiation research
The purpose of the present study was to reconstruct the energy spectrum of a poly-energetic neutron source using an algorithm developed based on an Adaptive Neuro-Fuzzy Inference System (ANFIS). ANFIS is a kind of artificial neural network based on t...

Efficient estimation of subdiffusive optical parameters in real time from spatially resolved reflectance by artificial neural networks.

Optics letters
Subdiffusive reflectance captured at short source-detector separations provides increased sensitivity to the scattering phase function and hence allows superficial probing of the tissue ultrastructure. Consequently, estimation of subdiffusive optical...