AIMC Topic: Computer Simulation

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Machine Learning for In Silico ADMET Prediction.

Methods in molecular biology (Clifton, N.J.)
ADMET (absorption, distribution, metabolism, excretion, and toxicity) describes a drug molecule's pharmacokinetics and pharmacodynamics properties. ADMET profile of a bioactive compound can impact its efficacy and safety. Moreover, efficacy and safet...

Validation of a Simulation Model for Robotic Sacrocolpopexy.

Female pelvic medicine & reconstructive surgery
OBJECTIVE: We sought to validate a simulation model for robotic sacrocolpopexy (RSCP) that includes multiple steps: presacral dissection/mesh attachment, vaginal mesh attachment, and peritoneal closure.

Physics-informed neural networks for one-dimensional sound field predictions with parameterized sources and impedance boundaries.

JASA express letters
Realistic sound is essential in virtual environments, such as computer games and mixed reality. Efficient and accurate numerical methods for pre-calculating acoustics have been developed over the last decade; however, pre-calculating acoustics makes ...

Past, present, and future of surgical simulation and perspective of a developing country: A narrative review.

JPMA. The Journal of the Pakistan Medical Association
Healthcare systems around the globe have been revolutionised in the last few decades, resulting in a greater need and demand for surgical education outside the operation theatres. Surgical education through simulations started around 2,500 years ago ...

AIPW: An R Package for Augmented Inverse Probability-Weighted Estimation of Average Causal Effects.

American journal of epidemiology
An increasing number of recent studies have suggested that doubly robust estimators with cross-fitting should be used when estimating causal effects with machine learning methods. However, not all existing programs that implement doubly robust estima...

Comparative analysis of molecular fingerprints in prediction of drug combination effects.

Briefings in bioinformatics
Application of machine and deep learning methods in drug discovery and cancer research has gained a considerable amount of attention in the past years. As the field grows, it becomes crucial to systematically evaluate the performance of novel computa...

Adaptive Cooperative Control for Hybrid FES-Robotic Upper Limb Devices: a Simulation Study.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Robotic systems and Functional Electrical Stimulation (FES) are common technologies exploited in motor rehabilitation. However, they present some limits. To overcome the weaknesses of both approaches, hybrid cooperative devices have been developed, w...

Assistive Sliding Mode Control of a Rehabilitation Robot with Automatic Weight Adjustment.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
There are approximately 13 million new stroke cases worldwide each year. Research has shown that robotics can provide practical and efficient solutions for expediting post-stroke patient recovery. This simulation study aimed to design a sliding mode ...

A disposable force regulation mechanism for throat swab robot.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Robots can protect healthcare workers from being infected by the COVID-19 and play a role in throat swab sampling operation. A critical requirement in this process is to maintain a constant force on the tissue for ensuring a safe and good sampling. I...