International journal of biological macromolecules
Mar 22, 2025
Cas proteins (CRISPR-associated protein) are the core components of the CRISPR-Cas system, playing critical roles in defending against foreign DNA and RNA invasions. Identifying Cas proteins can provide deeper insights into the immune mechanisms of t...
Autism Spectrum Disorder (ASD) is a complex neurological condition that impairs the ability to interact, communicate, and behave. It is becoming increasingly prevalent worldwide, with an increase in the number of young children diagnosed with ASD in ...
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Mar 19, 2025
BACKGROUND: In the HECKTOR 2022 challenge set [1], several state-of-the-art (SOTA, achieving best performance) deep learning models were introduced for predicting recurrence-free period (RFP) in head and neck cancer patients using PET and CT images.
The American Journal of dermatopathology
Mar 19, 2025
BACKGROUND: Lymph node (LN) assessment is a critical component in the staging and management of cutaneous melanoma. Traditional histopathological evaluation, supported by immunohistochemical staining, is the gold standard for detecting LN metastases....
BACKGROUND: The cytological diagnostic process of EUS-FNA smears is time-consuming and manpower-intensive, and the conclusion could be subjective and controversial. Moreover, the relative lack of cytopathologists has limited the widespread implementa...
BACKGROUND: Transcription factors (TFs) regulate the genes' expression by binding to DNA sequences. Aligned TFBSs of the same TF are seen as cis-regulatory motifs, and substantial computational efforts have been invested to find motifs. In recent yea...
Contrast-enhanced UTE-MRA provides detailed angiographic information but at the cost of prolonged scanning periods, which may impose moving artifacts and affect the promptness of diagnosis and treatment of time-sensitive diseases like stroke. This st...
Digital twins (DTs) are advancing biotechnology by providing digital models for drug discovery, digital health applications, and biological assets, including microorganisms. However, the hypothesis posits that implementing micro- and nanoscale DTs, e...
OBJECTIVE: To provide fully automatic scanner-independent 5-level categorization of the [I]FP-CIT uptake in striatal subregions in dopamine transporter SPECT.
Journal of molecular neuroscience : MN
Mar 15, 2025
Parkinson's disease recognition (PDR) involves identifying Parkinson's disease using clinical evaluations, imaging studies, and biomarkers, focusing on early symptoms like tremors, rigidity, and bradykinesia to facilitate timely treatment. However, d...
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