AIMC Topic: Corticobasal Degeneration

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Deep learning reveals disease-specific signatures of white matter pathology in tauopathies.

Acta neuropathologica communications Oct 21, 2021
Although pathology of tauopathies is characterized by abnormal tau protein aggregation in both gray and white matter regions of the brain, neuropathological investigations have generally focused on abnormalities in the cerebral cortex because the can...
Humans Brain Deep Learning Alzheimer Disease White Matter Supranuclear Palsy, Progressive Tauopathies Corticobasal Degeneration
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Machine learning-based decision tree classifier for the diagnosis of progressive supranuclear palsy and corticobasal degeneration.

Neuropathology and applied neurobiology Apr 7, 2021
AIMS: This study aimed to clarify the different topographical distribution of tau pathology between progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD) and establish a machine learning-based decision tree classifier.
Humans Machine Learning Brain Female Aged Aged, 80 and over Male Middle Aged Decision Trees Diagnosis, Differential tau Proteins Neurofibrillary Tangles Supranuclear Palsy, Progressive Nerve Degeneration Inclusion Bodies Corticobasal Degeneration
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