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Dacarbazine

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[Determination of dacarbazine in the urine of mice with melanoma by high performance liquid chromatography].

Se pu = Chinese journal of chromatography
Dacarbazine (DTIC) is a first-line chemotherapy drug that is widely used in clinical practice for malignant melanoma. DTIC is metabolized by the liver . Some drugs are excreted in urine in the form of a prototype. Hence, DTIC in urine can be monitore...

Effect of dacarbazine on CD44 in live melanoma cells as measured by atomic force microscopy-based nanoscopy.

International journal of nanomedicine
CD44 ligand-receptor interactions are known to be involved in regulating cell migration and tumor cell metastasis. High expression levels of CD44 correlate with a poor prognosis of melanoma patients. In order to understand not only the mechanistic ba...

Pseudo progression identification of glioblastoma with dictionary learning.

Computers in biology and medicine
OBJECTIVE: Although the use of temozolomide in chemoradiotherapy is effective, the challenging clinical problem of pseudo progression has been raised in brain tumor treatment. This study aims to distinguish pseudo progression from true progression.

MRI to MGMT: predicting methylation status in glioblastoma patients using convolutional recurrent neural networks.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing
Glioblastoma Multiforme (GBM), a malignant brain tumor, is among the most lethal of all cancers. Temozolomide is the primary chemotherapy treatment for patients diagnosed with GBM. The methylation status of the promoter or the enhancer regions of the...