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Hyaluronan Receptors

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[Astragalus polysaccharide combined with cisplatin inhibits growth of recurrent tumor and down-regulats the expression of CD44, CD62P and osteopontin in tumor tissues in mice bearing Lewis lung cancer].

Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 30626477
Objective To investigate the effects of Astragalus polysaccharide (APS) combined with cisplatin (DDP) on the pathological morphology of recurrent tumor and the expression of metastasis-related proteins CD44, CD62P and osteopontin (OPN) following Lewi...
Animals Astragalus Plant Carcinoma, Lewis Lung Cell Line, Tumor Cisplatin Hyaluronan Receptors Lung Neoplasms Mice Mice, Inbred C57BL Neoplasm Recurrence, Local Osteopontin P-Selectin Polysaccharides Random Allocation
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Effect of dacarbazine on CD44 in live melanoma cells as measured by atomic force microscopy-based nanoscopy.

International journal of nanomedicine 29296081
CD44 ligand-receptor interactions are known to be involved in regulating cell migration and tumor cell metastasis. High expression levels of CD44 correlate with a poor prognosis of melanoma patients. In order to understand not only the mechanistic ba...
Actins Animals Cell Line, Tumor Cell Survival Dacarbazine Hyaluronan Receptors Kinetics Melanoma Mice Microscopy, Atomic Force Quantum Dots Single Molecule Imaging Tubulin
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Machine Learning Integration with Single-Cell Transcriptome Sequencing Datasets Reveals the Impact of Tumor-Associated Neutrophils on the Immune Microenvironment and Immunotherapy Outcomes in Gastric Cancer.

International journal of molecular sciences 39684426
The characteristics of neutrophils play a crucial role in defining the tumor inflammatory environment. However, the function of tumor-associated neutrophils (TANs) in tumor immunity and their response to immune checkpoint inhibitors (ICIs) remains in...
Gene Expression Profiling Gene Expression Regulation, Neoplastic Humans Hyaluronan Receptors Immune Checkpoint Inhibitors Immunotherapy Machine Learning Neutrophils Prognosis Single-Cell Analysis Stomach Neoplasms Transcriptome Tumor Microenvironment
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MRI radiomics based on machine learning in high-grade gliomas as a promising tool for prediction of CD44 expression and overall survival.

Scientific reports 40032983
We aimed to predict CD44 expression and assess its prognostic significance in patients with high-grade gliomas (HGG) using non-invasive radiomics models based on machine learning. Enhanced magnetic resonance imaging, along with the corresponding gene...
Adult Aged Biomarkers, Tumor Brain Neoplasms Female Glioma Humans Hyaluronan Receptors Kaplan-Meier Estimate Machine Learning Magnetic Resonance Imaging Male Middle Aged Neoplasm Grading Prognosis Radiomics ROC Curve Support Vector Machine
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