In magnetic resonance imaging (MRI), variations in scan parameters and scanner specifications can result in differences in image appearance. To minimize these differences, harmonization in MRI has been suggested as a crucial image processing techniqu...
Diffusion MRI tractography technique enables non-invasive visualization of the white matter pathways in the brain. It plays a crucial role in neuroscience and clinical fields by facilitating the study of brain connectivity and neurological disorders....
The application of algorithm-based single-cell imaging techniques can visualize and analyze cellular heterogeneity. However, algorithm-based single-cell imaging techniques are severely limited by the high workload required to label single-cell images...
Journal of chemical information and modeling
Aug 11, 2025
Lead optimization in drug discovery faces the dual challenge of maintaining structural diversity while preserving core molecular features and optimizing the balance between biological activity and drug-like properties. To address these challenges, we...
Journal of chemical information and modeling
Aug 11, 2025
The processing of chemical information by computational intelligence methods faces the challenge of the structural complexity of molecular graphs. These graphs are not amenable to being represented in a suitable way for such methods. The most popular...
Journal of chemical information and modeling
Aug 11, 2025
Deep learning models for the quantitative structure-property relationship (QSPR) have traditionally encountered challenges related to limited interpretability and generalizability. In this study, we present the simplified molecular input line entry s...
Journal of chemical information and modeling
Aug 11, 2025
Noncoding RNAs (ncRNAs) interact with proteins, playing a crucial role in regulating gene expression and cellular functions. Accurate prediction of these interactions is essential for understanding biological processes and developing novel therapeuti...
BACKGROUND: Methotrexate (MTX) in the body can result in severe, potentially life-threatening side effects. As a result, it is imperative to establish a dependable, precise, and specific method for detecting MTX. However, conventional sensors often s...
Studies in health technology and informatics
Aug 7, 2025
In the process of patient diagnosis, non-invasive measurements are widely used due to their low risks and quick results. Electrocardiogram (ECG), as a non-invasive method to collect heart activities, is used to diagnose cardiac conditions. Analyzing ...
International journal of food microbiology
Aug 2, 2025
Owing to the unsound cold chain system in China, chilled beef's quality would be affected by psychrophilic bacteria, resulting in quality deterioration and corruption, which leads to food safety problems. In this study, the growth of Pseudomonas and ...
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