AIMC Topic: Deep Learning

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Deep Forest-based Prediction of Protein Subcellular Localization.

Current gene therapy
MOTIVATION: Knowledge of the correct protein subcellular localization is necessary for understanding the function of a protein and revealing the mechanism of many human diseases due to protein subcellular mislocalization, which is required before app...

Know When You Don't Know: A Robust Deep Learning Approach in the Presence of Unknown Phenotypes.

Assay and drug development technologies
Deep convolutional neural networks show outstanding performance in image-based phenotype classification given that all existing phenotypes are presented during the training of the network. However, in real-world high-content screening (HCS) experimen...

Machine Learning Methods in Computational Toxicology.

Methods in molecular biology (Clifton, N.J.)
Various methods of machine learning, supervised and unsupervised, linear and nonlinear, classification and regression, in combination with various types of molecular descriptors, both "handcrafted" and "data-driven," are considered in the context of ...

Deep Learning Role in Early Diagnosis of Prostate Cancer.

Technology in cancer research & treatment
The objective of this work is to develop a computer-aided diagnostic system for early diagnosis of prostate cancer. The presented system integrates both clinical biomarkers (prostate-specific antigen) and extracted features from diffusion-weighted ma...

A deep learning approach to estimate stress distribution: a fast and accurate surrogate of finite-element analysis.

Journal of the Royal Society, Interface
Structural finite-element analysis (FEA) has been widely used to study the biomechanics of human tissues and organs, as well as tissue-medical device interactions, and treatment strategies. However, patient-specific FEA models usually require complex...

Deep Learning-Based Noise Reduction Approach to Improve Speech Intelligibility for Cochlear Implant Recipients.

Ear and hearing
OBJECTIVE: We investigate the clinical effectiveness of a novel deep learning-based noise reduction (NR) approach under noisy conditions with challenging noise types at low signal to noise ratio (SNR) levels for Mandarin-speaking cochlear implant (CI...