BMC medical informatics and decision making
Jun 5, 2025
BACKGROUND: Prognostic prediction is crucial to guide individual treatment for patients with rectal cancer. We aimed to develop and validated a multitask deep learning model for predicting prognosis in rectal cancer patients.
OBJECTIVE: To create an automated PET/CT segmentation method and radiomics model to forecast Mismatch repair (MMR) and TP53 gene expression in endometrial cancer patients, and to examine the effect of gene expression variability on image texture feat...
Deep learning enables the modelling of high-resolution histopathology whole-slide images (WSI). Weakly supervised learning of tile-level data is typically applied for tasks where labels only exist on the patient or WSI level (e.g. patient outcomes or...
The pancreas is a gland in the abdomen that helps to produce hormones and digest food. The irregular development of tissues in the pancreas is termed as pancreatic cancer. Identification of pancreatic tumors early is significant for enhancing surviva...
INTRODUCTION: Congenital heart defect (CHD) is a significant, rapidly emerging global problem in child health and a leading cause of neonatal and childhood death. Prenatal detection of CHDs with the help of ultrasound allows better perinatal manageme...
Although genetic variant effects often interact nonadditively, strategies to uncover epistasis remain in their infancy. Here we develop low-signal signed iterative random forests to elucidate the complex genetic architecture of cardiac hypertrophy, u...
This study presents an advanced adaptive network steganography paradigm that integrates deep learning methodologies with multimedia video analysis to enhance the universality and security of network steganography practices. The proposed approach util...
Accurate preoperative diagnosis of papillary thyroid carcinoma (PTC) histological subtypes and lymph node metastasis is essential for formulating personalized treatment strategies. However, their preoperative diagnosis is challenged by the limited re...
Proceedings of the National Academy of Sciences of the United States of America
Jun 4, 2025
Characterizing the conformational ensemble of biomolecular systems is key to understand their functions. Cryoelectron microscopy (cryo-EM) captures two-dimensional snapshots of biomolecular ensembles, giving in principle access to thermodynamics. How...
BMC medical informatics and decision making
Jun 4, 2025
The detection and classification of blood cells are important in diagnosing and monitoring a variety of blood-related illnesses, such as anemia, leukemia, and infection, all of which may cause significant mortality. Accurate blood cell identification...
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